BRD-U33728988_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

109 genes differentially expressed following the BRD-U33728988_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AKR1C3 aldo-keto reductase family 1, member C3
AMOTL2 angiomotin like 2
AREG amphiregulin
ARID4B AT rich interactive domain 4B (RBP1-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ATG14 autophagy related 14
BCL6 B-cell CLL/lymphoma 6
BTG1 B-cell translocation gene 1, anti-proliferative
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
CHRDL1 chordin-like 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DPP4 dipeptidyl-peptidase 4
DST dystonin
DUSP6 dual specificity phosphatase 6
EGR2 early growth response 2
ESR1 estrogen receptor 1
GBP2 guanylate binding protein 2, interferon-inducible
GULP1 GULP, engulfment adaptor PTB domain containing 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IRF9 interferon regulatory factor 9
IRS1 insulin receptor substrate 1
KAT6B K(lysine) acetyltransferase 6B
KYNU kynureninase
LOC100505650 uncharacterized LOC100505650
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
NGRN neugrin, neurite outgrowth associated
NRIP1 nuclear receptor interacting protein 1
OSR2 odd-skipped related transciption factor 2
PDE4B phosphodiesterase 4B, cAMP-specific
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
QPCT glutaminyl-peptide cyclotransferase
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RNF144A ring finger protein 144A
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC38A1 solute carrier family 38, member 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM158 transmembrane protein 158 (gene/pseudogene)
TPD52L1 tumor protein D52-like 1
TXNIP thioredoxin interacting protein
TXNL4B thioredoxin-like 4B
WEE1 WEE1 G2 checkpoint kinase
ZFAND6 zinc finger, AN1-type domain 6

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AK1 adenylate kinase 1
AUTS2 autism susceptibility candidate 2
C6ORF62 chromosome 6 open reading frame 62
CANT1 calcium activated nucleotidase 1
CDC42 cell division cycle 42
COX11 COX11 cytochrome c oxidase copper chaperone
CRIP1 cysteine-rich protein 1 (intestinal)
CSRP1 cysteine and glycine-rich protein 1
CTBP2 C-terminal binding protein 2
CYB5A cytochrome b5 type A (microsomal)
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DOK4 docking protein 4
EIF5A eukaryotic translation initiation factor 5A
EMP3 epithelial membrane protein 3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM57A family with sequence similarity 57, member A
FKBP9 FK506 binding protein 9, 63 kDa
FOXF1 forkhead box F1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
KAZN kazrin, periplakin interacting protein
KRT4 keratin 4, type II
MAB21L2 mab-21-like 2 (C. elegans)
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
PCTP phosphatidylcholine transfer protein
PDLIM2 PDZ and LIM domain 2 (mystique)
PI3 peptidase inhibitor 3, skin-derived
PLBD1 phospholipase B domain containing 1
RAB31 RAB31, member RAS oncogene family
RALGDS ral guanine nucleotide dissociation stimulator
RCAN2 regulator of calcineurin 2
RPL27A ribosomal protein L27a
RPS11 ribosomal protein S11
S100A2 S100 calcium binding protein A2
SDC2 syndecan 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLPI secretory leukocyte peptidase inhibitor
SORBS3 sorbin and SH3 domain containing 3
STXBP1 syntaxin binding protein 1
TIMP3 TIMP metallopeptidase inhibitor 3
TPM4 tropomyosin 4
TSKU tsukushi, small leucine rich proteoglycan
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)