BRD-U32365159_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-U32365159_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AQP9 aquaporin 9
CXCL10 chemokine (C-X-C motif) ligand 10
DDIT4 DNA-damage-inducible transcript 4
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IGL immunoglobulin lambda locus
KDM3A lysine (K)-specific demethylase 3A
NRIP3 nuclear receptor interacting protein 3
PTPRE protein tyrosine phosphatase, receptor type, E
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RORA RAR-related orphan receptor A
TCF4 transcription factor 4
TGFBI transforming growth factor, beta-induced, 68kDa
TSKU tsukushi, small leucine rich proteoglycan
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ALDOB aldolase B, fructose-bisphosphate
APOD apolipoprotein D
CCNE2 cyclin E2
DPP4 dipeptidyl-peptidase 4
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
IFITM2 interferon induced transmembrane protein 2
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
LAMB1 laminin, beta 1
MAGEA3 melanoma antigen family A3
MYOF myoferlin
RFC2 replication factor C (activator 1) 2, 40kDa
ZNF185 zinc finger protein 185 (LIM domain)