BRD-U29336476_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

239 genes differentially expressed following the BRD-U29336476_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ACKR3 atypical chemokine receptor 3
ANKRD10 ankyrin repeat domain 10
APLP2 amyloid beta (A4) precursor-like protein 2
ARHGAP32 Rho GTPase activating protein 32
ASPN asporin
ASS1 argininosuccinate synthase 1
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
AZIN1 antizyme inhibitor 1
BAMBI BMP and activin membrane-bound inhibitor
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRD2 bromodomain containing 2
BSG basigin (Ok blood group)
BTG1 B-cell translocation gene 1, anti-proliferative
CA2 carbonic anhydrase II
CADM1 cell adhesion molecule 1
CALD1 caldesmon 1
CCNG2 cyclin G2
CD46 CD46 molecule, complement regulatory protein
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CECR1 cat eye syndrome chromosome region, candidate 1
CFB complement factor B
CHGB chromogranin B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC2B C-type lectin domain family 2, member B
COL11A1 collagen, type XI, alpha 1
COL15A1 collagen, type XV, alpha 1
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
COMP cartilage oligomeric matrix protein
CPE carboxypeptidase E
CRIP2 cysteine-rich protein 2
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
DCN decorin
DEPTOR DEP domain containing MTOR-interacting protein
DMTF1 cyclin D binding myb-like transcription factor 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
EIF5 eukaryotic translation initiation factor 5
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FABP4 fatty acid binding protein 4, adipocyte
FAM117A family with sequence similarity 117, member A
FAM69A family with sequence similarity 69, member A
GAS1 growth arrest-specific 1
GCH1 GTP cyclohydrolase 1
GLUL glutamate-ammonia ligase
GPX3 glutathione peroxidase 3
H2BFS H2B histone family, member S (pseudogene)
HBP1 HMG-box transcription factor 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HILPDA hypoxia inducible lipid droplet-associated
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IDS iduronate 2-sulfatase
IFI27 interferon, alpha-inducible protein 27
IFNGR1 interferon gamma receptor 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IL2RG interleukin 2 receptor, gamma
INSIG1 insulin induced gene 1
ITM2A integral membrane protein 2A
ITM2B integral membrane protein 2B
KDM3A lysine (K)-specific demethylase 3A
LAMP2 lysosomal-associated membrane protein 2
LUM lumican
MAN1A1 mannosidase, alpha, class 1A, member 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
METTL7A methyltransferase like 7A
MFAP5 microfibrillar associated protein 5
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MN1 meningioma (disrupted in balanced translocation) 1
MTSS1 metastasis suppressor 1
MYO1D myosin ID
MZB1 marginal zone B and B1 cell-specific protein
NDFIP1 Nedd4 family interacting protein 1
NDRG1 N-myc downstream regulated 1
NFIL3 nuclear factor, interleukin 3 regulated
NLRP2 NLR family, pyrin domain containing 2
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCSK1 proprotein convertase subtilisin/kexin type 1
PDLIM3 PDZ and LIM domain 3
PEG10 paternally expressed 10
PGK1 phosphoglycerate kinase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RB1CC1 RB1-inducible coiled-coil 1
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF167 ring finger protein 167
RRM2 ribonucleotide reductase M2
RSRP1 arginine/serine-rich protein 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCPEP1 serine carboxypeptidase 1
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SPARCL1 SPARC-like 1 (hevin)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SQLE squalene epoxidase
SQSTM1 sequestosome 1
SRSF7 serine/arginine-rich splicing factor 7
ST18 suppression of tumorigenicity 18, zinc finger
STOM stomatin
STX1A syntaxin 1A (brain)
SULF1 sulfatase 1
TCF4 transcription factor 4
THBS2 thrombospondin 2
THY1 Thy-1 cell surface antigen
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM259 transmembrane protein 259
TMEM59 transmembrane protein 59
TOB1 transducer of ERBB2, 1
TOX3 TOX high mobility group box family member 3
TPD52 tumor protein D52
TPP1 tripeptidyl peptidase I
TRAM1 translocation associated membrane protein 1
TRIL TLR4 interactor with leucine-rich repeats
TSPAN13 tetraspanin 13
UBE2A ubiquitin-conjugating enzyme E2A
WDR26 WD repeat domain 26
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZDHHC11 zinc finger, DHHC-type containing 11
ZFAND5 zinc finger, AN1-type domain 5

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
ADORA2B adenosine A2b receptor
ALCAM activated leukocyte cell adhesion molecule
BEX1 brain expressed, X-linked 1
BIN1 bridging integrator 1
CARD10 caspase recruitment domain family, member 10
CBR3 carbonyl reductase 3
CCDC86 coiled-coil domain containing 86
CHMP6 charged multivesicular body protein 6
CIAPIN1 cytokine induced apoptosis inhibitor 1
CTPS1 CTP synthase 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYTH1 cytohesin 1
DCLK1 doublecortin-like kinase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLC1 DLC1 Rho GTPase activating protein
DUSP4 dual specificity phosphatase 4
EDN1 endothelin 1
EGFR epidermal growth factor receptor
EMP1 epithelial membrane protein 1
EMP3 epithelial membrane protein 3
ERAP2 endoplasmic reticulum aminopeptidase 2
ERBB2 erb-b2 receptor tyrosine kinase 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FBL fibrillarin
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
FPGS folylpolyglutamate synthase
FXYD5 FXYD domain containing ion transport regulator 5
FZD2 frizzled class receptor 2
GLIPR1 GLI pathogenesis-related 1
GPR171 G protein-coupled receptor 171
GTPBP8 GTP-binding protein 8 (putative)
HOXB2 homeobox B2
HOXB6 homeobox B6
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGHD immunoglobulin heavy constant delta
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
JUN jun proto-oncogene
KEAP1 kelch-like ECH-associated protein 1
KLHL9 kelch-like family member 9
LAPTM4B lysosomal protein transmembrane 4 beta
LPAR1 lysophosphatidic acid receptor 1
LXN latexin
MAGEF1 melanoma antigen family F1
MAP1B microtubule-associated protein 1B
MAP2K3 mitogen-activated protein kinase kinase 3
MECOM MDS1 and EVI1 complex locus
MET MET proto-oncogene, receptor tyrosine kinase
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MOK MOK protein kinase
MRPL23 mitochondrial ribosomal protein L23
MYC v-myc avian myelocytomatosis viral oncogene homolog
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NPTX1 neuronal pentraxin I
NRG1 neuregulin 1
OLFM4 olfactomedin 4
OXTR oxytocin receptor
PDGFC platelet derived growth factor C
PDLIM2 PDZ and LIM domain 2 (mystique)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAC8 placenta-specific 8
PLAUR plasminogen activator, urokinase receptor
PLK2 polo-like kinase 2
PNN pinin, desmosome associated protein
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPIF peptidylprolyl isomerase F
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTX3 pentraxin 3, long
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RCAN1 regulator of calcineurin 1
RFC2 replication factor C (activator 1) 2, 40kDa
RHOBTB3 Rho-related BTB domain containing 3
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SMAGP small cell adhesion glycoprotein
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SORBS3 sorbin and SH3 domain containing 3
SORD sorbitol dehydrogenase
TACSTD2 tumor-associated calcium signal transducer 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM4SF1 transmembrane 4 L six family member 1
TRIP6 thyroid hormone receptor interactor 6
UGCG UDP-glucose ceramide glucosyltransferase
VCAN versican
ZIC1 Zic family member 1
ZNF586 zinc finger protein 586
ZNF91 zinc finger protein 91