BRD-U22633929_XMD11-85H_MDAMB231_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-U22633929_XMD11-85H_MDAMB231_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACPP acid phosphatase, prostate
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AMD1 adenosylmethionine decarboxylase 1
ARG2 arginase 2
BASP1 brain abundant, membrane attached signal protein 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD24 CD24 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD9 CD9 molecule
CRISP3 cysteine-rich secretory protein 3
CTSS cathepsin S
CXCL9 chemokine (C-X-C motif) ligand 9
DEGS1 delta(4)-desaturase, sphingolipid 1
ESRP1 epithelial splicing regulatory protein 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KLF4 Kruppel-like factor 4 (gut)
MSMB microseminoprotein, beta-
NOTCH2 notch 2
QPCT glutaminyl-peptide cyclotransferase
RHOB ras homolog family member B
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SORBS2 sorbin and SH3 domain containing 2
SPTBN1 spectrin, beta, non-erythrocytic 1
TARP TCR gamma alternate reading frame protein
TM4SF1 transmembrane 4 L six family member 1

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRG2 adhesion G protein-coupled receptor G2
AMDHD2 amidohydrolase domain containing 2
ASS1 argininosuccinate synthase 1
BEX1 brain expressed, X-linked 1
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL6A1 collagen, type VI, alpha 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP1 fatty acid binding protein 1, liver
FAS Fas cell surface death receptor
FCGBP Fc fragment of IgG binding protein
FOXF1 forkhead box F1
GAS1 growth arrest-specific 1
GMDS GDP-mannose 4,6-dehydratase
GOLGA8A golgin A8 family, member A
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI6 interferon, alpha-inducible protein 6
IGKC immunoglobulin kappa constant
ISG15 ISG15 ubiquitin-like modifier
ITGB4 integrin, beta 4
JMJD6 jumonji domain containing 6
KDM5D lysine (K)-specific demethylase 5D
KRT19 keratin 19, type I
KRT20 keratin 20, type I
LAMB3 laminin, beta 3
LAMP5 lysosomal-associated membrane protein family, member 5
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGALS4 lectin, galactoside-binding, soluble, 4
LRRC17 leucine rich repeat containing 17
LTBP1 latent transforming growth factor beta binding protein 1
MAPT microtubule-associated protein tau
MCUR1 mitochondrial calcium uniporter regulator 1
MFAP4 microfibrillar-associated protein 4
MUC5B mucin 5B, oligomeric mucus/gel-forming
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NES nestin
NUP85 nucleoporin 85kDa
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OLFM4 olfactomedin 4
PAN2 PAN2 poly(A) specific ribonuclease subunit
PLAT plasminogen activator, tissue
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RPS4Y1 ribosomal protein S4, Y-linked 1
SCG2 secretogranin II
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SPINK1 serine peptidase inhibitor, Kazal type 1
SRPX sushi-repeat containing protein, X-linked
TFF3 trefoil factor 3 (intestinal)
TM4SF4 transmembrane 4 L six family member 4
VAV3 vav 3 guanine nucleotide exchange factor