BRD-U22633929_XMD11-85H_HEPG2_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

113 genes differentially expressed following the BRD-U22633929_XMD11-85H_HEPG2_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADRB2 adrenoceptor beta 2, surface
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
AUTS2 autism susceptibility candidate 2
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
CD8A CD8a molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COCH cochlin
COL1A1 collagen, type I, alpha 1
COL9A3 collagen, type IX, alpha 3
CRIP1 cysteine-rich protein 1 (intestinal)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DNM1 dynamin 1
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EML3 echinoderm microtubule associated protein like 3
EMP3 epithelial membrane protein 3
ENO2 enolase 2 (gamma, neuronal)
EPHB2 EPH receptor B2
ETV1 ets variant 1
FAM46A family with sequence similarity 46, member A
FUCA1 fucosidase, alpha-L- 1, tissue
GPX3 glutathione peroxidase 3
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HP haptoglobin
IGFBP3 insulin-like growth factor binding protein 3
IGHMBP2 immunoglobulin mu binding protein 2
KCNK1 potassium channel, two pore domain subfamily K, member 1
KIAA1598
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF9 Kruppel-like factor 9
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
LGALS8 lectin, galactoside-binding, soluble, 8
LTF lactotransferrin
LYN LYN proto-oncogene, Src family tyrosine kinase
LYST lysosomal trafficking regulator
MAP7 microtubule-associated protein 7
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP9 matrix metallopeptidase 9
MTSS1 metastasis suppressor 1
NAV3 neuron navigator 3
OXSR1 oxidative stress responsive 1
PDZK1IP1 PDZK1 interacting protein 1
PIEZO2 piezo-type mechanosensitive ion channel component 2
RAD23B RAD23 homolog B (S. cerevisiae)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RELN reelin
RGS2 regulator of G-protein signaling 2
RHOA ras homolog family member A
RHOBTB3 Rho-related BTB domain containing 3
RXRA retinoid X receptor, alpha
SCRN1 secernin 1
SEPP1 selenoprotein P, plasma, 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SF1 splicing factor 1
SFN stratifin
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SNCAIP synuclein, alpha interacting protein
SOX9 SRY (sex determining region Y)-box 9
SPEN spen family transcriptional repressor
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSBP2 single-stranded DNA binding protein 2
STC2 stanniocalcin 2
TARP TCR gamma alternate reading frame protein
TM4SF1 transmembrane 4 L six family member 1
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADGRG6 adhesion G protein-coupled receptor G6
AIM1 absent in melanoma 1
AREG amphiregulin
C1ORF54 chromosome 1 open reading frame 54
CXCL14 chemokine (C-X-C motif) ligand 14
EDNRB endothelin receptor type B
FAM69A family with sequence similarity 69, member A
FBP1 fructose-1,6-bisphosphatase 1
FGFR2 fibroblast growth factor receptor 2
FXYD3 FXYD domain containing ion transport regulator 3
GPNMB glycoprotein (transmembrane) nmb
HIST1H2AC histone cluster 1, H2ac
HIST1H4C histone cluster 1, H4c
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI16 interferon, gamma-inducible protein 16
IFI27 interferon, alpha-inducible protein 27
IGFBP5 insulin-like growth factor binding protein 5
KCTD12 potassium channel tetramerization domain containing 12
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KRT20 keratin 20, type I
NEFL neurofilament, light polypeptide
PAM peptidylglycine alpha-amidating monooxygenase
PELI1 pellino E3 ubiquitin protein ligase 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PROSC proline synthetase co-transcribed homolog (bacterial)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK1 serine peptidase inhibitor, Kazal type 1
SQRDL sulfide quinone reductase-like (yeast)
SRPX sushi-repeat containing protein, X-linked
STOM stomatin
TNFRSF21 tumor necrosis factor receptor superfamily, member 21