BRD-U08759356_EI-346_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

50 genes differentially expressed following the BRD-U08759356_EI-346_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ADAMDEC1 ADAM-like, decysin 1
ANXA5 annexin A5
ARF4 ADP-ribosylation factor 4
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATXN1 ataxin 1
CALU calumenin
CREB3L2 cAMP responsive element binding protein 3-like 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DMBT1 deleted in malignant brain tumors 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
FHL1 four and a half LIM domains 1
GFPT1 glutamine--fructose-6-phosphate transaminase 1
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LINC00341 long intergenic non-protein coding RNA 341
MFAP5 microfibrillar associated protein 5
MGST3 microsomal glutathione S-transferase 3
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDE4DIP phosphodiesterase 4D interacting protein
PPAP2B phosphatidic acid phosphatase type 2B
RCAN1 regulator of calcineurin 1
RNASE4 ribonuclease, RNase A family, 4
SCRG1 stimulator of chondrogenesis 1
SEC24D SEC24 family member D
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP1 secreted frizzled-related protein 1
SLC35B1 solute carrier family 35, member B1
SLC38A1 solute carrier family 38, member 1
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TPBG trophoblast glycoprotein
TPSAB1 tryptase alpha/beta 1
TSPAN7 tetraspanin 7
WIPI1 WD repeat domain, phosphoinositide interacting 1
XBP1 X-box binding protein 1
XPOT exportin, tRNA

decreased expression

Symbol Name
CD93 CD93 molecule
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
HSPA1A heat shock 70kDa protein 1A
ISG15 ISG15 ubiquitin-like modifier
KRT23 keratin 23, type I
PCCB propionyl CoA carboxylase, beta polypeptide
STEAP1 six transmembrane epithelial antigen of the prostate 1