BRD-U07805514_saracatinib_PC3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

88 genes differentially expressed following the BRD-U07805514_saracatinib_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCND2 cyclin D2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLIC5 chloride intracellular channel 5
COCH cochlin
CYBA cytochrome b-245, alpha polypeptide
CYCS cytochrome c, somatic
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP5 dual specificity phosphatase 5
EMP3 epithelial membrane protein 3
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM134B family with sequence similarity 134, member B
GAS7 growth arrest-specific 7
GDF15 growth differentiation factor 15
GPX3 glutathione peroxidase 3
HOXA5 homeobox A5
KANK2 KN motif and ankyrin repeat domains 2
L1TD1 LINE-1 type transposase domain containing 1
LYN LYN proto-oncogene, Src family tyrosine kinase
METTL7A methyltransferase like 7A
NLRP2 NLR family, pyrin domain containing 2
OLFM4 olfactomedin 4
PDZK1IP1 PDZK1 interacting protein 1
PLAC8 placenta-specific 8
PLS1 plastin 1
PRKCB protein kinase C, beta
PROM1 prominin 1
RBP1 retinol binding protein 1, cellular
REG1A regenerating islet-derived 1 alpha
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
THBS1 thrombospondin 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AMIGO2 adhesion molecule with Ig-like domain 2
ANGPT1 angiopoietin 1
CALML5 calmodulin-like 5
CCND1 cyclin D1
CD200 CD200 molecule
CD59 CD59 molecule, complement regulatory protein
CENPE centromere protein E, 312kDa
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL3A1 collagen, type III, alpha 1
COL6A3 collagen, type VI, alpha 3
CXCL9 chemokine (C-X-C motif) ligand 9
DSP desmoplakin
DUSP2 dual specificity phosphatase 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
EGR2 early growth response 2
FAM69A family with sequence similarity 69, member A
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
GBP2 guanylate binding protein 2, interferon-inducible
GJA1 gap junction protein, alpha 1, 43kDa
GRAMD3 GRAM domain containing 3
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT6B keratin 6B, type II
LAMA4 laminin, alpha 4
LTF lactotransferrin
MAOB monoamine oxidase B
MMP9 matrix metallopeptidase 9
MPZL2 myelin protein zero-like 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PAM peptidylglycine alpha-amidating monooxygenase
PERP PERP, TP53 apoptosis effector
PFN2 profilin 2
PLS3 plastin 3
RGCC regulator of cell cycle
RPS5 ribosomal protein S5
RTN1 reticulon 1
S100P S100 calcium binding protein P
SCGB2A1 secretoglobin, family 2A, member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SNAI2 snail family zinc finger 2
SOX9 SRY (sex determining region Y)-box 9
SPRR1B small proline-rich protein 1B
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TM9SF3 transmembrane 9 superfamily member 3
TPM2 tropomyosin 2 (beta)
TPM4 tropomyosin 4