BRD-M64432851_S1042_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-M64432851_S1042_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
BASP1 brain abundant, membrane attached signal protein 1
CPB1 carboxypeptidase B1 (tissue)
DDIT4 DNA-damage-inducible transcript 4
FDFT1 farnesyl-diphosphate farnesyltransferase 1
HIST1H1C histone cluster 1, H1c
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
LDLR low density lipoprotein receptor
LEPROT leptin receptor overlapping transcript
LXN latexin
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MSMO1 methylsterol monooxygenase 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SQLE squalene epoxidase
TST thiosulfate sulfurtransferase (rhodanese)
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
CCNA2 cyclin A2
COL4A2 collagen, type IV, alpha 2
DES desmin
GAL galanin/GMAP prepropeptide
IGFBP3 insulin-like growth factor binding protein 3
KIAA0101 KIAA0101
KIF20A kinesin family member 20A
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLK2 polo-like kinase 2
RBP1 retinol binding protein 1, cellular
RRM2 ribonucleotide reductase M2
SLPI secretory leukocyte peptidase inhibitor
THBD thrombomodulin
TNNC1 troponin C type 1 (slow)