BRD-K99545815_PF-562271_HS578T_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

69 genes differentially expressed following the BRD-K99545815_PF-562271_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRL1 adhesion G protein-coupled receptor L1
APLP2 amyloid beta (A4) precursor-like protein 2
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
COL15A1 collagen, type XV, alpha 1
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL8 chemokine (C-X-C motif) ligand 8
DPP4 dipeptidyl-peptidase 4
FAS Fas cell surface death receptor
FHL1 four and a half LIM domains 1
FNBP1 formin binding protein 1
HBB hemoglobin, beta
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
PERP PERP, TP53 apoptosis effector
PLAGL1 pleiomorphic adenoma gene-like 1
PROM1 prominin 1
SPON1 spondin 1, extracellular matrix protein
SPP1 secreted phosphoprotein 1
SYNGR1 synaptogyrin 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
VCAN versican

decreased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
AIM2 absent in melanoma 2
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
AQP3 aquaporin 3 (Gill blood group)
AURKB aurora kinase B
BAZ1A bromodomain adjacent to zinc finger domain, 1A
CAPN2 calpain 2, (m/II) large subunit
CCNE2 cyclin E2
CD24 CD24 molecule
CDC45 cell division cycle 45
CST1 cystatin SN
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL14 chemokine (C-X-C motif) ligand 14
CYTL1 cytokine-like 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
EIF5 eukaryotic translation initiation factor 5
FZD2 frizzled class receptor 2
IFI27 interferon, alpha-inducible protein 27
IGL immunoglobulin lambda locus
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KDM5D lysine (K)-specific demethylase 5D
KIF20A kinesin family member 20A
MARCKS myristoylated alanine-rich protein kinase C substrate
NAV2 neuron navigator 2
NMT1 N-myristoyltransferase 1
NRG1 neuregulin 1
PDLIM1 PDZ and LIM domain 1
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSRC1 proline/serine-rich coiled-coil 1
RGS4 regulator of G-protein signaling 4
RHOB ras homolog family member B
RHOBTB3 Rho-related BTB domain containing 3
SCGB2A2 secretoglobin, family 2A, member 2
SEC14L1 SEC14-like 1 (S. cerevisiae)
SNAP25 synaptosomal-associated protein, 25kDa
SRSF2 serine/arginine-rich splicing factor 2
TLR4 toll-like receptor 4
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZNF22 zinc finger protein 22