BRD-K99502566_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

103 genes differentially expressed following the BRD-K99502566_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
ALDOC aldolase C, fructose-bisphosphate
APOD apolipoprotein D
ASPH aspartate beta-hydroxylase
ASRGL1 asparaginase like 1
C3 complement component 3
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CES1 carboxylesterase 1
CFD complement factor D (adipsin)
CORO1A coronin, actin binding protein, 1A
CSTA cystatin A (stefin A)
CXCL14 chemokine (C-X-C motif) ligand 14
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
FADS1 fatty acid desaturase 1
FAXDC2 fatty acid hydroxylase domain containing 2
FBLN1 fibulin 1
FGF13 fibroblast growth factor 13
FN1 fibronectin 1
FOXO4 forkhead box O4
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GLRX glutaredoxin (thioltransferase)
GULP1 GULP, engulfment adaptor PTB domain containing 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMOX1 heme oxygenase 1
IER3 immediate early response 3
IFI16 interferon, gamma-inducible protein 16
IFI27 interferon, alpha-inducible protein 27
IFITM1 interferon induced transmembrane protein 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INSIG1 insulin induced gene 1
KIF5C kinesin family member 5C
KRT19 keratin 19, type I
LAMB1 laminin, beta 1
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LRRC17 leucine rich repeat containing 17
MDK midkine (neurite growth-promoting factor 2)
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMD monocyte to macrophage differentiation-associated
MSX1 msh homeobox 1
MYH11 myosin, heavy chain 11, smooth muscle
OLFM4 olfactomedin 4
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PERP PERP, TP53 apoptosis effector
PLA2G16 phospholipase A2, group XVI
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLIN2 perilipin 2
PLXNC1 plexin C1
PROM1 prominin 1
PYGL phosphorylase, glycogen, liver
QPRT quinolinate phosphoribosyltransferase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RND3 Rho family GTPase 3
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RTN1 reticulon 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCPEP1 serine carboxypeptidase 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP4 secreted frizzled-related protein 4
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SNAI2 snail family zinc finger 2
STC1 stanniocalcin 1
SYNGR3 synaptogyrin 3
SYT1 synaptotagmin I
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TRD T cell receptor delta locus
TRIM2 tripartite motif containing 2
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VIM vimentin
VLDLR very low density lipoprotein receptor
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
ATAD2 ATPase family, AAA domain containing 2
ATF5 activating transcription factor 5
CA2 carbonic anhydrase II
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GRWD1 glutamate-rich WD repeat containing 1
HAT1 histone acetyltransferase 1
ICAM3 intercellular adhesion molecule 3
IFRD2 interferon-related developmental regulator 2
LIG1 ligase I, DNA, ATP-dependent
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POSTN periostin, osteoblast specific factor
PPIF peptidylprolyl isomerase F
SHCBP1 SHC SH2-domain binding protein 1
SRM spermidine synthase