BRD-K99311057_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K99311057_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CCND2 cyclin D2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHI3L2 chitinase 3-like 2
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
DHRS2 dehydrogenase/reductase (SDR family) member 2
DUSP6 dual specificity phosphatase 6
EZR ezrin
GATA3 GATA binding protein 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
ICAM1 intercellular adhesion molecule 1
IL6 interleukin 6
INSIG1 insulin induced gene 1
MAP7 microtubule-associated protein 7
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MUC5B mucin 5B, oligomeric mucus/gel-forming
NCAM1 neural cell adhesion molecule 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NRCAM neuronal cell adhesion molecule
S100A8 S100 calcium binding protein A8
TACSTD2 tumor-associated calcium signal transducer 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNIP1 TNFAIP3 interacting protein 1
TRH thyrotropin-releasing hormone

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
CASP7 caspase 7, apoptosis-related cysteine peptidase
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
DCLK1 doublecortin-like kinase 1
FGFR2 fibroblast growth factor receptor 2
GPC4 glypican 4
NREP neuronal regeneration related protein
PBX3 pre-B-cell leukemia homeobox 3
PLEKHA5 pleckstrin homology domain containing, family A member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SOCS2 suppressor of cytokine signaling 2
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TWIST1 twist family bHLH transcription factor 1