BRD-K99252563_QL-XII-47_MDAMB231_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K99252563_QL-XII-47_MDAMB231_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AQP3 aquaporin 3 (Gill blood group)
ARL4C ADP-ribosylation factor-like 4C
ARMCX2 armadillo repeat containing, X-linked 2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CNN3 calponin 3, acidic
COLEC12 collectin sub-family member 12
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DLK1 delta-like 1 homolog (Drosophila)
DPP4 dipeptidyl-peptidase 4
EGR2 early growth response 2
FGFR3 fibroblast growth factor receptor 3
FOXF1 forkhead box F1
FZD7 frizzled class receptor 7
GDF15 growth differentiation factor 15
GOLT1B golgi transport 1B
HES1 hes family bHLH transcription factor 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL1R1 interleukin 1 receptor, type I
ITM2C integral membrane protein 2C
KLK11 kallikrein-related peptidase 11
LYPD1 LY6/PLAUR domain containing 1
NFIL3 nuclear factor, interleukin 3 regulated
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PDGFC platelet derived growth factor C
PECR peroxisomal trans-2-enoyl-CoA reductase
PEG10 paternally expressed 10
PHLDA1 pleckstrin homology-like domain, family A, member 1
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
STC2 stanniocalcin 2
SYNJ2 synaptojanin 2
TACSTD2 tumor-associated calcium signal transducer 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSC22D3 TSC22 domain family, member 3
TSPAN8 tetraspanin 8
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ASS1 argininosuccinate synthase 1
CDC42 cell division cycle 42
CHGB chromogranin B
CXCL9 chemokine (C-X-C motif) ligand 9
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DUSP3 dual specificity phosphatase 3
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
GLUL glutamate-ammonia ligase
HHEX hematopoietically expressed homeobox
HIRA histone cell cycle regulator
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IGHM immunoglobulin heavy constant mu
LUM lumican
LXN latexin
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAN1A1 mannosidase, alpha, class 1A, member 1
MMP11 matrix metallopeptidase 11
MMP9 matrix metallopeptidase 9
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NRCAM neuronal cell adhesion molecule
PECAM1 platelet/endothelial cell adhesion molecule 1
RAD51C RAD51 paralog C
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
THBS2 thrombospondin 2
TMEM176B transmembrane protein 176B
TMEM45A transmembrane protein 45A
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TSPAN13 tetraspanin 13
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28