BRD-K99252563_QL-XII-47_MCF7_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K99252563_QL-XII-47_MCF7_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADD3 adducin 3 (gamma)
APMAP adipocyte plasma membrane associated protein
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
C7 complement component 7
CA12 carbonic anhydrase XII
CCP110 centriolar coiled coil protein 110kDa
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLMN calmin (calponin-like, transmembrane)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
E2F2 E2F transcription factor 2
EPCAM epithelial cell adhesion molecule
FOXG1 forkhead box G1
FZD7 frizzled class receptor 7
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MYLK myosin light chain kinase
NQO1 NAD(P)H dehydrogenase, quinone 1
PALLD palladin, cytoskeletal associated protein
PAM peptidylglycine alpha-amidating monooxygenase
PDGFRL platelet-derived growth factor receptor-like
POU4F1 POU class 4 homeobox 1
PTK7 protein tyrosine kinase 7 (inactive)
RAP1GAP RAP1 GTPase activating protein
S100P S100 calcium binding protein P
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SOBP sine oculis binding protein homolog (Drosophila)
SOX4 SRY (sex determining region Y)-box 4
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
TSKU tsukushi, small leucine rich proteoglycan

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
AQP1 aquaporin 1 (Colton blood group)
CBS cystathionine-beta-synthase
CD36 CD36 molecule (thrombospondin receptor)
CDKN2A cyclin-dependent kinase inhibitor 2A
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL5A2 collagen, type V, alpha 2
DENND1B DENN/MADD domain containing 1B
DMBT1 deleted in malignant brain tumors 1
EDNRB endothelin receptor type B
EGLN3 egl-9 family hypoxia-inducible factor 3
EPHA3 EPH receptor A3
HOXB7 homeobox B7
KDR kinase insert domain receptor
LGALS4 lectin, galactoside-binding, soluble, 4
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAN2A1 mannosidase, alpha, class 2A, member 1
MEF2C myocyte enhancer factor 2C
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NEFL neurofilament, light polypeptide
NNMT nicotinamide N-methyltransferase
NR4A2 nuclear receptor subfamily 4, group A, member 2
ODC1 ornithine decarboxylase 1
PDZK1IP1 PDZK1 interacting protein 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PLA2G16 phospholipase A2, group XVI
PRDX2 peroxiredoxin 2
PRUNE2 prune homolog 2 (Drosophila)
RGS4 regulator of G-protein signaling 4
SCG2 secretogranin II
SEC61G Sec61 gamma subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX10 sorting nexin 10
SPON2 spondin 2, extracellular matrix protein
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
XIST X inactive specific transcript (non-protein coding)