BRD-K99252563_QL-XII-47_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K99252563_QL-XII-47_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
CHIC2 cysteine-rich hydrophobic domain 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EIF5A eukaryotic translation initiation factor 5A
GADD45A growth arrest and DNA-damage-inducible, alpha
HCAR3 hydroxycarboxylic acid receptor 3
IER3 immediate early response 3
JUN jun proto-oncogene
KDM3A lysine (K)-specific demethylase 3A
LPAR6 lysophosphatidic acid receptor 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMP7 matrix metallopeptidase 7
OPN3 opsin 3
RHOB ras homolog family member B
RND3 Rho family GTPase 3
SCYL3 SCY1-like 3 (S. cerevisiae)
SOX9 SRY (sex determining region Y)-box 9
TBX3 T-box 3
TES testin LIM domain protein
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1
TRIB1 tribbles pseudokinase 1
TRIM2 tripartite motif containing 2

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
CAPG capping protein (actin filament), gelsolin-like
CTSB cathepsin B
F2R coagulation factor II (thrombin) receptor
FAS Fas cell surface death receptor
FERMT1 fermitin family member 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
LGALS1 lectin, galactoside-binding, soluble, 1
MXRA5 matrix-remodelling associated 5
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SPP1 secreted phosphoprotein 1
SYT1 synaptotagmin I
TMEM47 transmembrane protein 47