BRD-K99252563_QL-XII-47_BT20_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-K99252563_QL-XII-47_BT20_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANKRD10 ankyrin repeat domain 10
AQP3 aquaporin 3 (Gill blood group)
ASNS asparagine synthetase (glutamine-hydrolyzing)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CALML5 calmodulin-like 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CHI3L2 chitinase 3-like 2
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CKAP4 cytoskeleton-associated protein 4
COG5 component of oligomeric golgi complex 5
COL15A1 collagen, type XV, alpha 1
COL3A1 collagen, type III, alpha 1
CRYAB crystallin, alpha B
CXCL13 chemokine (C-X-C motif) ligand 13
DCLK1 doublecortin-like kinase 1
DHRS7 dehydrogenase/reductase (SDR family) member 7
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLK1 delta-like 1 homolog (Drosophila)
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DST dystonin
DUSP14 dual specificity phosphatase 14
EGFR epidermal growth factor receptor
EMP1 epithelial membrane protein 1
EMP3 epithelial membrane protein 3
ENO2 enolase 2 (gamma, neuronal)
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
H1F0 H1 histone family, member 0
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IER3 immediate early response 3
IGFBP4 insulin-like growth factor binding protein 4
KLF4 Kruppel-like factor 4 (gut)
KRT1 keratin 1, type II
KRT16 keratin 16, type I
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT81 keratin 81, type II
LIF leukemia inhibitory factor
LMO4 LIM domain only 4
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARCKS myristoylated alanine-rich protein kinase C substrate
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NAMPT nicotinamide phosphoribosyltransferase
NAV3 neuron navigator 3
PLAUR plasminogen activator, urokinase receptor
PTCH1 patched 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SFRP1 secreted frizzled-related protein 1
SOX9 SRY (sex determining region Y)-box 9
SPRY2 sprouty homolog 2 (Drosophila)
STMN2 stathmin 2
TRDV3 T cell receptor delta variable 3
TSPAN7 tetraspanin 7
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AIM1 absent in melanoma 1
BTN3A3 butyrophilin, subfamily 3, member A3
C6ORF62 chromosome 6 open reading frame 62
CCNG2 cyclin G2
CFB complement factor B
CFD complement factor D (adipsin)
CFI complement factor I
CLDN3 claudin 3
CRABP2 cellular retinoic acid binding protein 2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
FN1 fibronectin 1
HIST1H2BG histone cluster 1, H2bg
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
INSIG1 insulin induced gene 1
ISYNA1 inositol-3-phosphate synthase 1
KRT19 keratin 19, type I
MDK midkine (neurite growth-promoting factor 2)
MYL9 myosin, light chain 9, regulatory
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
PDIA3 protein disulfide isomerase family A, member 3
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSCA prostate stem cell antigen
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PXDN peroxidasin
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SH3BGRL SH3 domain binding glutamate-rich protein like
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
THBS2 thrombospondin 2
TMEM47 transmembrane protein 47
TRIM22 tripartite motif containing 22
WFS1 Wolfram syndrome 1 (wolframin)
YME1L1 YME1-like 1 ATPase