BRD-K98824517_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

100 genes differentially expressed following the BRD-K98824517_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ATF3 activating transcription factor 3
BAMBI BMP and activin membrane-bound inhibitor
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BTG1 B-cell translocation gene 1, anti-proliferative
BTG3 BTG family, member 3
CCNE2 cyclin E2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
COL11A1 collagen, type XI, alpha 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DEPTOR DEP domain containing MTOR-interacting protein
EFNA1 ephrin-A1
EGR1 early growth response 1
EIF5 eukaryotic translation initiation factor 5
EMP1 epithelial membrane protein 1
EPS8 epidermal growth factor receptor pathway substrate 8
FZD6 frizzled class receptor 6
GADD45A growth arrest and DNA-damage-inducible, alpha
GDF15 growth differentiation factor 15
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HK2 hexokinase 2
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IL6 interleukin 6
ISG20 interferon stimulated exonuclease gene 20kDa
JUNB jun B proto-oncogene
KCTD12 potassium channel tetramerization domain containing 12
KDM3A lysine (K)-specific demethylase 3A
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NDRG1 N-myc downstream regulated 1
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRIP1 nuclear receptor interacting protein 1
PDZD2 PDZ domain containing 2
PELI1 pellino E3 ubiquitin protein ligase 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
RIOK3 RIO kinase 3
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A2 secretoglobin, family 2A, member 2
SERTAD2 SERTA domain containing 2
SIK1 salt-inducible kinase 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SORBS2 sorbin and SH3 domain containing 2
SOX9 SRY (sex determining region Y)-box 9
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST18 suppression of tumorigenicity 18, zinc finger
STC1 stanniocalcin 1
TACSTD2 tumor-associated calcium signal transducer 2
TGFA transforming growth factor, alpha
TM4SF1 transmembrane 4 L six family member 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM28 ADAM metallopeptidase domain 28
AKAP7 A kinase (PRKA) anchor protein 7
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
APMAP adipocyte plasma membrane associated protein
BCHE butyrylcholinesterase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCNF cyclin F
CD24 CD24 molecule
CDC20 cell division cycle 20
CETN2 centrin, EF-hand protein, 2
COL4A6 collagen, type IV, alpha 6
CTTN cortactin
ECI2 enoyl-CoA delta isomerase 2
FAM3C family with sequence similarity 3, member C
FBXO9 F-box protein 9
GLIPR1 GLI pathogenesis-related 1
HOXA10 homeobox A10
KANK2 KN motif and ankyrin repeat domains 2
MICALL1 MICAL-like 1
MYLK myosin light chain kinase
N4BP2L2 NEDD4 binding protein 2-like 2
NPIPB3 nuclear pore complex interacting protein family, member B3
PALLD palladin, cytoskeletal associated protein
REEP1 receptor accessory protein 1
RPL27A ribosomal protein L27a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
S100A2 S100 calcium binding protein A2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC38A1 solute carrier family 38, member 1
TBL1X transducin (beta)-like 1X-linked
VCAN versican
WRB tryptophan rich basic protein