BRD-K98490050_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K98490050_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AREG amphiregulin
ARL4C ADP-ribosylation factor-like 4C
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLIC5 chloride intracellular channel 5
DCN decorin
DDB2 damage-specific DNA binding protein 2, 48kDa
DENND1B DENN/MADD domain containing 1B
ECM1 extracellular matrix protein 1
FABP4 fatty acid binding protein 4, adipocyte
FAS Fas cell surface death receptor
GAS6 growth arrest-specific 6
GPM6B glycoprotein M6B
IRF6 interferon regulatory factor 6
MIR22HG MIR22 host gene
MPO myeloperoxidase
NR4A3 nuclear receptor subfamily 4, group A, member 3
PDGFA platelet-derived growth factor alpha polypeptide
PTPRE protein tyrosine phosphatase, receptor type, E
RGCC regulator of cell cycle
SDC4 syndecan 4
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

decreased expression

Symbol Name
BAG3 BCL2-associated athanogene 3
CHI3L2 chitinase 3-like 2
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
HOXC10 homeobox C10
KIF14 kinesin family member 14
KIF2C kinesin family member 2C
LBR lamin B receptor
MYC v-myc avian myelocytomatosis viral oncogene homolog
PBK PDZ binding kinase
PDLIM5 PDZ and LIM domain 5
SPTBN1 spectrin, beta, non-erythrocytic 1
TM4SF1 transmembrane 4 L six family member 1
TNC tenascin C
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2S ubiquitin-conjugating enzyme E2S