BRD-K98203492_GSK-J4_PC3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-K98203492_GSK-J4_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPT1 angiopoietin 1
ARHGAP29 Rho GTPase activating protein 29
ATG3 autophagy related 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BASP1 brain abundant, membrane attached signal protein 1
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CNN1 calponin 1, basic, smooth muscle
COL9A3 collagen, type IX, alpha 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
ECM1 extracellular matrix protein 1
FBLN1 fibulin 1
GLUL glutamate-ammonia ligase
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IRS1 insulin receptor substrate 1
KIAA0753 KIAA0753
KLK11 kallikrein-related peptidase 11
LAMC2 laminin, gamma 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MGP matrix Gla protein
MMP7 matrix metallopeptidase 7
MSLN mesothelin
MSMB microseminoprotein, beta-
NPIPB3 nuclear pore complex interacting protein family, member B3
NPTX2 neuronal pentraxin II
NPY1R neuropeptide Y receptor Y1
NRCAM neuronal cell adhesion molecule
OSBPL10 oxysterol binding protein-like 10
PBX3 pre-B-cell leukemia homeobox 3
PCP4 Purkinje cell protein 4
PDLIM1 PDZ and LIM domain 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
SDC2 syndecan 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP1 secreted frizzled-related protein 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SOD3 superoxide dismutase 3, extracellular
SORBS1 sorbin and SH3 domain containing 1
SPON2 spondin 2, extracellular matrix protein
SYNM synemin, intermediate filament protein
TACSTD2 tumor-associated calcium signal transducer 2
TARBP1 TAR (HIV-1) RNA binding protein 1
TMSB15A thymosin beta 15a
TPBG trophoblast glycoprotein
TRIM29 tripartite motif containing 29

decreased expression

Symbol Name
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAT catalase
CCL20 chemokine (C-C motif) ligand 20
CRISP3 cysteine-rich secretory protein 3
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DDAH1 dimethylarginine dimethylaminohydrolase 1
DEFB1 defensin, beta 1
ENO1 enolase 1, (alpha)
ERBB2IP erbb2 interacting protein
EREG epiregulin
FGG fibrinogen gamma chain
HLF hepatic leukemia factor
IGHM immunoglobulin heavy constant mu
LAPTM4B lysosomal protein transmembrane 4 beta
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LRRC15 leucine rich repeat containing 15
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
NUTF2 nuclear transport factor 2
PLCB4 phospholipase C, beta 4
PLS1 plastin 1
PLS3 plastin 3
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
VDAC1 voltage-dependent anion channel 1
WT1 Wilms tumor 1
ZEB2 zinc finger E-box binding homeobox 2