BRD-K98173387_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-K98173387_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
BASP1 brain abundant, membrane attached signal protein 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLU clusterin
DST dystonin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EML3 echinoderm microtubule associated protein like 3
FADS1 fatty acid desaturase 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
HMOX1 heme oxygenase 1
KYNU kynureninase
LTBP3 latent transforming growth factor beta binding protein 3
NR2F2 nuclear receptor subfamily 2, group F, member 2
PLTP phospholipid transfer protein
PTGES prostaglandin E synthase
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1

decreased expression

Symbol Name
CA2 carbonic anhydrase II
CRABP1 cellular retinoic acid binding protein 1
CRABP2 cellular retinoic acid binding protein 2
CXADR coxsackie virus and adenovirus receptor
ENOPH1 enolase-phosphatase 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
PTN pleiotrophin
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RGCC regulator of cell cycle
SCGB2A2 secretoglobin, family 2A, member 2
TFF1 trefoil factor 1
TPD52 tumor protein D52