BRD-K97863768_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K97863768_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ANXA4 annexin A4
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
AREG amphiregulin
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BAX BCL2-associated X protein
BLNK B-cell linker
CD9 CD9 molecule
CPA3 carboxypeptidase A3 (mast cell)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
DDB2 damage-specific DNA binding protein 2, 48kDa
DDIT4 DNA-damage-inducible transcript 4
DEFB1 defensin, beta 1
EPHA2 EPH receptor A2
F5 coagulation factor V (proaccelerin, labile factor)
FAS Fas cell surface death receptor
FDXR ferredoxin reductase
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
KLK5 kallikrein-related peptidase 5
LGALS1 lectin, galactoside-binding, soluble, 1
MSMO1 methylsterol monooxygenase 1
PDGFA platelet-derived growth factor alpha polypeptide
PLXNB2 plexin B2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PYCARD PYD and CARD domain containing
S100A8 S100 calcium binding protein A8
SESN1 sestrin 1
SFN stratifin
SYNGR1 synaptogyrin 1
TP53I3 tumor protein p53 inducible protein 3
TRIM22 tripartite motif containing 22
TST thiosulfate sulfurtransferase (rhodanese)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAMP8 vesicle-associated membrane protein 8
YPEL5 yippee-like 5 (Drosophila)
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
C3 complement component 3
C6ORF62 chromosome 6 open reading frame 62
CDC42 cell division cycle 42
CDK6 cyclin-dependent kinase 6
CP ceruloplasmin (ferroxidase)
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF5 eukaryotic translation initiation factor 5
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KPNB1 karyopherin (importin) beta 1
LIMCH1 LIM and calponin homology domains 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NFIB nuclear factor I/B
ODC1 ornithine decarboxylase 1
PLK1 polo-like kinase 1
PODXL podocalyxin-like
PRKCD protein kinase C, delta
PTP4A2 protein tyrosine phosphatase type IVA, member 2
TNC tenascin C
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2S ubiquitin-conjugating enzyme E2S