BRD-K97764662_PD-173074_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K97764662_PD-173074_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
COL11A1 collagen, type XI, alpha 1
CXCL12 chemokine (C-X-C motif) ligand 12
DACT1 dishevelled-binding antagonist of beta-catenin 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
GAS1 growth arrest-specific 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GREM1 gremlin 1, DAN family BMP antagonist
ITM2C integral membrane protein 2C
KRT81 keratin 81, type II
PLXNC1 plexin C1
PRKCQ protein kinase C, theta
RGS1 regulator of G-protein signaling 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
XAF1 XIAP associated factor 1
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADRB2 adrenoceptor beta 2, surface
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOD apolipoprotein D
ARHGAP29 Rho GTPase activating protein 29
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
AUTS2 autism susceptibility candidate 2
CDH3 cadherin 3, type 1, P-cadherin (placental)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHN1 chimerin 1
CLEC3B C-type lectin domain family 3, member B
COL1A2 collagen, type I, alpha 2
DCLK1 doublecortin-like kinase 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL3 dihydropyrimidinase-like 3
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
EGR2 early growth response 2
EMP1 epithelial membrane protein 1
EREG epiregulin
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FOSL1 FOS-like antigen 1
FRZB frizzled-related protein
GAGE3 G antigen 3
GPM6A glycoprotein M6A
HOPX HOP homeobox
HOXB7 homeobox B7
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
JUN jun proto-oncogene
LAMC2 laminin, gamma 2
LEPR leptin receptor
LHFP lipoma HMGIC fusion partner
LMO3 LIM domain only 3 (rhombotin-like 2)
MALL mal, T-cell differentiation protein-like
MET MET proto-oncogene, receptor tyrosine kinase
MGP matrix Gla protein
MMP7 matrix metallopeptidase 7
MPZL2 myelin protein zero-like 2
MYO1B myosin IB
NES nestin
NPTX2 neuronal pentraxin II
NRN1 neuritin 1
NT5E 5'-nucleotidase, ecto (CD73)
PCLO piccolo presynaptic cytomatrix protein
PDLIM2 PDZ and LIM domain 2 (mystique)
PECAM1 platelet/endothelial cell adhesion molecule 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRAME preferentially expressed antigen in melanoma
PRKCH protein kinase C, eta
RGCC regulator of cell cycle
RTN1 reticulon 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SNAP25 synaptosomal-associated protein, 25kDa
SORBS2 sorbin and SH3 domain containing 2
SORBS3 sorbin and SH3 domain containing 3
SOX9 SRY (sex determining region Y)-box 9
STC1 stanniocalcin 1
SYT1 synaptotagmin I
TCF4 transcription factor 4
TM4SF1 transmembrane 4 L six family member 1
TSPAN1 tetraspanin 1
TSPAN7 tetraspanin 7
TSPAN8 tetraspanin 8
WASF1 WAS protein family, member 1