BRD-K97764662_3044_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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26 genes differentially expressed following the BRD-K97764662_3044_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOB aldolase B, fructose-bisphosphate
ALDOC aldolase C, fructose-bisphosphate
ANXA1 annexin A1
CD59 CD59 molecule, complement regulatory protein
DDIT4 DNA-damage-inducible transcript 4
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
NCAM1 neural cell adhesion molecule 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
QPCT glutaminyl-peptide cyclotransferase
RRAGD Ras-related GTP binding D
S100A12 S100 calcium binding protein A12
TF transferrin
TPM4 tropomyosin 4
WIPI1 WD repeat domain, phosphoinositide interacting 1
WLS wntless Wnt ligand secretion mediator

decreased expression

Symbol Name
BIRC5 baculoviral IAP repeat containing 5
CA12 carbonic anhydrase XII
CCNB2 cyclin B2
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
GRWD1 glutamate-rich WD repeat containing 1
KIF14 kinesin family member 14
KIF2C kinesin family member 2C
NR2F2 nuclear receptor subfamily 2, group F, member 2
ODC1 ornithine decarboxylase 1
TOP2A topoisomerase (DNA) II alpha 170kDa