BRD-K97365803_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

90 genes differentially expressed following the BRD-K97365803_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARMCX1 armadillo repeat containing, X-linked 1
BLNK B-cell linker
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRD8 bromodomain containing 8
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAV2 caveolin 2
CCNG2 cyclin G2
CDK19 cyclin-dependent kinase 19
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHMP1B charged multivesicular body protein 1B
CIRBP cold inducible RNA binding protein
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLEC2B C-type lectin domain family 2, member B
CLIC4 chloride intracellular channel 4
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
GNB5 guanine nucleotide binding protein (G protein), beta 5
H1F0 H1 histone family, member 0
H2BFS H2B histone family, member S (pseudogene)
HBP1 HMG-box transcription factor 1
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HNMT histamine N-methyltransferase
HOPX HOP homeobox
HOXA5 homeobox A5
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
JUND jun D proto-oncogene
KLHDC2 kelch domain containing 2
KLHL24 kelch-like family member 24
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MEF2C myocyte enhancer factor 2C
MTUS1 microtubule associated tumor suppressor 1
MXI1 MAX interactor 1, dimerization protein
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEFH neurofilament, heavy polypeptide
NPC2 Niemann-Pick disease, type C2
RB1CC1 RB1-inducible coiled-coil 1
RSRP1 arginine/serine-rich protein 1
SEPP1 selenoprotein P, plasma, 1
SKAP2 src kinase associated phosphoprotein 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
TMSB15A thymosin beta 15a
TXNL4B thioredoxin-like 4B
UBE2B ubiquitin-conjugating enzyme E2B
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WIPI1 WD repeat domain, phosphoinositide interacting 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

decreased expression

Symbol Name
CD14 CD14 molecule
CDC25A cell division cycle 25A
CKAP4 cytoskeleton-associated protein 4
CTPS1 CTP synthase 1
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DKC1 dyskeratosis congenita 1, dyskerin
DPH2 DPH2 homolog (S. cerevisiae)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM216A family with sequence similarity 216, member A
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GRWD1 glutamate-rich WD repeat containing 1
HBEGF heparin-binding EGF-like growth factor
LTF lactotransferrin
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP16 NOP16 nucleolar protein
NXT1 nuclear transport factor 2-like export factor 1
PLBD1 phospholipase B domain containing 1
PNO1 partner of NOB1 homolog (S. cerevisiae)
POSTN periostin, osteoblast specific factor
PPIF peptidylprolyl isomerase F
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRMT1 protein arginine methyltransferase 1
RGS2 regulator of G-protein signaling 2
S100A8 S100 calcium binding protein A8
SFRP1 secreted frizzled-related protein 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SORD sorbitol dehydrogenase
SRPRB signal recognition particle receptor, B subunit
STEAP3 STEAP family member 3, metalloreductase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF3 trefoil factor 3 (intestinal)
TMEM109 transmembrane protein 109
TMEM176A transmembrane protein 176A
TRIM14 tripartite motif containing 14