BRD-K97365803_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K97365803_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
CCNG2 cyclin G2
CDK7 cyclin-dependent kinase 7
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
GATA6 GATA binding protein 6
H1F0 H1 histone family, member 0
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BC histone cluster 1, H2bc
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BH histone cluster 1, H2bh
HIST1H2BK histone cluster 1, H2bk
HMGB2 high mobility group box 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
PNKP polynucleotide kinase 3'-phosphatase
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SHB Src homology 2 domain containing adaptor protein B
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
BAG3 BCL2-associated athanogene 3
BCHE butyrylcholinesterase
C8ORF4 chromosome 8 open reading frame 4
CDC25A cell division cycle 25A
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FAM57A family with sequence similarity 57, member A
HSPA1A heat shock 70kDa protein 1A
HSPH1 heat shock 105kDa/110kDa protein 1
JMJD6 jumonji domain containing 6
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
PODXL podocalyxin-like
RBMS1 RNA binding motif, single stranded interacting protein 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A2 S100 calcium binding protein A2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
TRAPPC3 trafficking protein particle complex 3