BRD-K97309399_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K97309399_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
AMIGO2 adhesion molecule with Ig-like domain 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CPB1 carboxypeptidase B1 (tissue)
CSTA cystatin A (stefin A)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
ELOVL6 ELOVL fatty acid elongase 6
FADS1 fatty acid desaturase 1
FDPS farnesyl diphosphate synthase
FGFR3 fibroblast growth factor receptor 3
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GLRX glutaredoxin (thioltransferase)
GULP1 GULP, engulfment adaptor PTB domain containing 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IDI1 isopentenyl-diphosphate delta isomerase 1
IER5 immediate early response 5
KLK6 kallikrein-related peptidase 6
KRT6B keratin 6B, type II
LDLR low density lipoprotein receptor
MNDA myeloid cell nuclear differentiation antigen
NEB nebulin
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PHLDA2 pleckstrin homology-like domain, family A, member 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SQLE squalene epoxidase
SRGN serglycin
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TPD52L1 tumor protein D52-like 1
TRIB2 tribbles pseudokinase 2
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
FAM107A family with sequence similarity 107, member A
LPL lipoprotein lipase
NFIB nuclear factor I/B
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
TSPAN13 tetraspanin 13