BRD-K97309399_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

86 genes differentially expressed following the BRD-K97309399_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ANK2 ankyrin 2, neuronal
ANPEP alanyl (membrane) aminopeptidase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
CD163 CD163 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CLIC4 chloride intracellular channel 4
CLIC5 chloride intracellular channel 5
CPM carboxypeptidase M
CYFIP2 cytoplasmic FMR1 interacting protein 2
DDIT3 DNA-damage-inducible transcript 3
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP1 fatty acid binding protein 1, liver
GARS glycyl-tRNA synthetase
GDF15 growth differentiation factor 15
GLRX glutaredoxin (thioltransferase)
GPR137B G protein-coupled receptor 137B
GREM1 gremlin 1, DAN family BMP antagonist
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IDI1 isopentenyl-diphosphate delta isomerase 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1R1 interleukin 1 receptor, type I
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1A1 mannosidase, alpha, class 1A, member 1
MERTK MER proto-oncogene, tyrosine kinase
MFAP5 microfibrillar associated protein 5
MMD monocyte to macrophage differentiation-associated
MSMO1 methylsterol monooxygenase 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
NT5E 5'-nucleotidase, ecto (CD73)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLS1 plastin 1
PSAT1 phosphoserine aminotransferase 1
PTER phosphotriesterase related
QPRT quinolinate phosphoribosyltransferase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SQSTM1 sequestosome 1
SRPX sushi-repeat containing protein, X-linked
SYBU syntabulin (syntaxin-interacting)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGIF1 TGFB-induced factor homeobox 1
VTCN1 V-set domain containing T cell activation inhibitor 1
WISP2 WNT1 inducible signaling pathway protein 2

decreased expression

Symbol Name
CADM1 cell adhesion molecule 1
CALML3 calmodulin-like 3
CD24 CD24 molecule
COPS7A COP9 signalosome subunit 7A
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GJA1 gap junction protein, alpha 1, 43kDa
HACD3 3-hydroxyacyl-CoA dehydratase 3
KDM5D lysine (K)-specific demethylase 5D
KLK11 kallikrein-related peptidase 11
KRT13 keratin 13, type I
KRT6A keratin 6A, type II
MARCKS myristoylated alanine-rich protein kinase C substrate
MRPS2 mitochondrial ribosomal protein S2
MUC5B mucin 5B, oligomeric mucus/gel-forming
PITX1 paired-like homeodomain 1
RPS4Y1 ribosomal protein S4, Y-linked 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNX7 sorting nexin 7
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
TMPRSS11E transmembrane protease, serine 11E
TPM1 tropomyosin 1 (alpha)