BRD-K96704648_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K96704648_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
ALOX5 arachidonate 5-lipoxygenase
ANXA1 annexin A1
AREG amphiregulin
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
C1ORF106 chromosome 1 open reading frame 106
CD24 CD24 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CORO1A coronin, actin binding protein, 1A
COTL1 coactosin-like F-actin binding protein 1
DDIT4 DNA-damage-inducible transcript 4
DEFB1 defensin, beta 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLK1 delta-like 1 homolog (Drosophila)
FAM107A family with sequence similarity 107, member A
FLNA filamin A, alpha
FTH1 ferritin, heavy polypeptide 1
GPM6A glycoprotein M6A
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRT19 keratin 19, type I
KRT23 keratin 23, type I
MAOB monoamine oxidase B
MAP3K5 mitogen-activated protein kinase kinase kinase 5
NEFH neurofilament, heavy polypeptide
NGRN neugrin, neurite outgrowth associated
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PELI1 pellino E3 ubiquitin protein ligase 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAUR plasminogen activator, urokinase receptor
RGCC regulator of cell cycle
RRAGD Ras-related GTP binding D
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SOX9 SRY (sex determining region Y)-box 9
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
SYNM synemin, intermediate filament protein
TXNIP thioredoxin interacting protein
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WASF3 WAS protein family, member 3
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
AMDHD2 amidohydrolase domain containing 2
AR androgen receptor
ATF5 activating transcription factor 5
CDKN2A cyclin-dependent kinase inhibitor 2A
CYB561 cytochrome b561
FKBP11 FK506 binding protein 11, 19 kDa
GPNMB glycoprotein (transmembrane) nmb
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP7 insulin-like growth factor binding protein 7
LUM lumican
MMP11 matrix metallopeptidase 11
NNMT nicotinamide N-methyltransferase
PLK2 polo-like kinase 2
S100A8 S100 calcium binding protein A8
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SNRPE small nuclear ribonucleoprotein polypeptide E
TIMP3 TIMP metallopeptidase inhibitor 3