BRD-K96354014_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

20 genes differentially expressed following the BRD-K96354014_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ASNS asparagine synthetase (glutamine-hydrolyzing)
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
GDF15 growth differentiation factor 15
IGFBP3 insulin-like growth factor binding protein 3
NQO1 NAD(P)H dehydrogenase, quinone 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
WDR45 WD repeat domain 45

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BCL6 B-cell CLL/lymphoma 6
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GJA1 gap junction protein, alpha 1, 43kDa
HN1 hematological and neurological expressed 1
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
NUSAP1 nucleolar and spindle associated protein 1
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
TLR4 toll-like receptor 4