BRD-K96083840_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K96083840_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ANKRD10 ankyrin repeat domain 10
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
CKAP4 cytoskeleton-associated protein 4
CREB1 cAMP responsive element binding protein 1
CTNND1 catenin (cadherin-associated protein), delta 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
EHBP1 EH domain binding protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM129A family with sequence similarity 129, member A
FAM69A family with sequence similarity 69, member A
HIST1H2BD histone cluster 1, H2bd
HLA-B major histocompatibility complex, class I, B
HLA-G major histocompatibility complex, class I, G
INHBB inhibin, beta B
KANK1 KN motif and ankyrin repeat domains 1
NAMPT nicotinamide phosphoribosyltransferase
NEFH neurofilament, heavy polypeptide
NEK7 NIMA-related kinase 7
OXTR oxytocin receptor
PEA15 phosphoprotein enriched in astrocytes 15
PLAC8 placenta-specific 8
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RAI14 retinoic acid induced 14
RGS2 regulator of G-protein signaling 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
TACSTD2 tumor-associated calcium signal transducer 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM2 tripartite motif containing 2

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADIRF adipogenesis regulatory factor
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
C1ORF54 chromosome 1 open reading frame 54
CALB1 calbindin 1, 28kDa
CD24 CD24 molecule
CDC45 cell division cycle 45
CDCA4 cell division cycle associated 4
CFD complement factor D (adipsin)
CLEC11A C-type lectin domain family 11, member A
COCH cochlin
COL2A1 collagen, type II, alpha 1
COL6A2 collagen, type VI, alpha 2
COLEC11 collectin sub-family member 11
CRIP1 cysteine-rich protein 1 (intestinal)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
CYTL1 cytokine-like 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP6 dual specificity phosphatase 6
FAM46C family with sequence similarity 46, member C
FGF13 fibroblast growth factor 13
GPM6B glycoprotein M6B
GPX7 glutathione peroxidase 7
GSTM3 glutathione S-transferase mu 3 (brain)
HOXC6 homeobox C6
IFI27 interferon, alpha-inducible protein 27
IL1R2 interleukin 1 receptor, type II
JAM3 junctional adhesion molecule 3
LAMP5 lysosomal-associated membrane protein family, member 5
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
NPTX2 neuronal pentraxin II
PENK proenkephalin
PRR4 proline rich 4 (lacrimal)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RCN3 reticulocalbin 3, EF-hand calcium binding domain
REG1A regenerating islet-derived 1 alpha
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS11 ribosomal protein S11
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRY2 sprouty homolog 2 (Drosophila)
STOM stomatin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TM4SF4 transmembrane 4 L six family member 4
TMEM47 transmembrane protein 47
TOR1A torsin family 1, member A (torsin A)
TSPYL5 TSPY-like 5