BRD-K95921201_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

45 genes differentially expressed following the BRD-K95921201_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACACB acetyl-CoA carboxylase beta
ACLY ATP citrate lyase
BICC1 BicC family RNA binding protein 1
CAPN2 calpain 2, (m/II) large subunit
CCNG2 cyclin G2
CD24 CD24 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFB complement factor B
COL14A1 collagen, type XIV, alpha 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FBN1 fibrillin 1
H1FX H1 histone family, member X
HIST1H2BD histone cluster 1, H2bd
KCTD12 potassium channel tetramerization domain containing 12
KLF2 Kruppel-like factor 2
LPIN1 lipin 1
MSMO1 methylsterol monooxygenase 1
PEG10 paternally expressed 10
PITX1 paired-like homeodomain 1
PNMA2 paraneoplastic Ma antigen 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFRP1 secreted frizzled-related protein 1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
TPBG trophoblast glycoprotein
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BCHE butyrylcholinesterase
C4BPA complement component 4 binding protein, alpha
CKS2 CDC28 protein kinase regulatory subunit 2
COL4A5 collagen, type IV, alpha 5
CXCL9 chemokine (C-X-C motif) ligand 9
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
LYZ lysozyme
MMP9 matrix metallopeptidase 9
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
RBM3 RNA binding motif (RNP1, RRM) protein 3
RPS27L ribosomal protein S27-like