BRD-K95673125_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K95673125_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
CLIC5 chloride intracellular channel 5
FAM69A family with sequence similarity 69, member A
FOXF1 forkhead box F1
GAL galanin/GMAP prepropeptide
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
LGALS4 lectin, galactoside-binding, soluble, 4
LOC100505650 uncharacterized LOC100505650
LPAR1 lysophosphatidic acid receptor 1
MAP7 microtubule-associated protein 7
MN1 meningioma (disrupted in balanced translocation) 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PRKCI protein kinase C, iota
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SHB Src homology 2 domain containing adaptor protein B
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
ST18 suppression of tumorigenicity 18, zinc finger
TLE4 transducin-like enhancer of split 4
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble

decreased expression

Symbol Name
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CXCL8 chemokine (C-X-C motif) ligand 8
GDF15 growth differentiation factor 15
GGCT gamma-glutamylcyclotransferase
H3F3B H3 histone, family 3B (H3.3B)
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SORD sorbitol dehydrogenase
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)