BRD-K95655893_VEGF Receptor 3 Kinase Inhibitor, MAZ51_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K95655893_VEGF Receptor 3 Kinase Inhibitor, MAZ51_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CAV1 caveolin 1, caveolae protein, 22kDa
CERS6 ceramide synthase 6
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
EREG epiregulin
F13A1 coagulation factor XIII, A1 polypeptide
FOSL1 FOS-like antigen 1
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HMOX1 heme oxygenase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
LAMP1 lysosomal-associated membrane protein 1
MEF2C myocyte enhancer factor 2C
MIR22HG MIR22 host gene
RAP1GAP RAP1 GTPase activating protein
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CDK1 cyclin-dependent kinase 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EED embryonic ectoderm development
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FANCI Fanconi anemia, complementation group I
FOXG1 forkhead box G1
H2AFX H2A histone family, member X
KIAA0101 KIAA0101
KIF2C kinesin family member 2C
LYZ lysozyme
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MELK maternal embryonic leucine zipper kinase
MKI67 marker of proliferation Ki-67
NME4 NME/NM23 nucleoside diphosphate kinase 4
RFC3 replication factor C (activator 1) 3, 38kDa
RRM1 ribonucleotide reductase M1
SMC2 structural maintenance of chromosomes 2
TFPI2 tissue factor pathway inhibitor 2
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C