BRD-K95655893_VEGF Receptor 3 Kinase Inhibitor, MAZ51_HT29_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-K95655893_VEGF Receptor 3 Kinase Inhibitor, MAZ51_HT29_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CAV1 caveolin 1, caveolae protein, 22kDa
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CDA cytidine deaminase
CHMP6 charged multivesicular body protein 6
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLTB clathrin, light chain B
COL4A2 collagen, type IV, alpha 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP22 dual specificity phosphatase 22
EPB41L3 erythrocyte membrane protein band 4.1-like 3
GAL galanin/GMAP prepropeptide
GPX3 glutathione peroxidase 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPB8 heat shock 22kDa protein 8
IFI27 interferon, alpha-inducible protein 27
IGFBP6 insulin-like growth factor binding protein 6
IGHMBP2 immunoglobulin mu binding protein 2
IGL immunoglobulin lambda locus
IL6ST interleukin 6 signal transducer
ISCU iron-sulfur cluster assembly enzyme
ITM2A integral membrane protein 2A
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JADE2 jade family PHD finger 2
JCHAIN joining chain of multimeric IgA and IgM
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KRT14 keratin 14, type I
KRT18 keratin 18, type I
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGEA12 melanoma antigen family A12
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MIR22HG MIR22 host gene
MPP1 membrane protein, palmitoylated 1, 55kDa
MSN moesin
NELL2 NEL-like 2 (chicken)
NMU neuromedin U
NPY1R neuropeptide Y receptor Y1
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM4 PDZ and LIM domain 4
PITX1 paired-like homeodomain 1
PLAC8 placenta-specific 8
PXDN peroxidasin
REEP5 receptor accessory protein 5
RGS1 regulator of G-protein signaling 1
SELL selectin L
SERINC5 serine incorporator 5
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TPM1 tropomyosin 1 (alpha)
TRIM14 tripartite motif containing 14
XPO7 exportin 7
ZBTB18 zinc finger and BTB domain containing 18
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
ADM adrenomedullin
ANXA4 annexin A4
ARMCX2 armadillo repeat containing, X-linked 2
C10ORF10 chromosome 10 open reading frame 10
CCNF cyclin F
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDK1 cyclin-dependent kinase 1
CRIP1 cysteine-rich protein 1 (intestinal)
CTBP2 C-terminal binding protein 2
DUSP6 dual specificity phosphatase 6
EMX2 empty spiracles homeobox 2
FAM60A family with sequence similarity 60, member A
GINS2 GINS complex subunit 2 (Psf2 homolog)
HILPDA hypoxia inducible lipid droplet-associated
HIST1H4C histone cluster 1, H4c
HOXA5 homeobox A5
KCTD12 potassium channel tetramerization domain containing 12
LRRC41 leucine rich repeat containing 41
MME membrane metallo-endopeptidase
NOTCH3 notch 3
NREP neuronal regeneration related protein
NUSAP1 nucleolar and spindle associated protein 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SULF1 sulfatase 1
TCF4 transcription factor 4
TKTL1 transketolase-like 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOP2A topoisomerase (DNA) II alpha 170kDa
TOPBP1 topoisomerase (DNA) II binding protein 1
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C