BRD-K95655893_VEGF Receptor 3 Kinase Inhibitor, MAZ51_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

72 genes differentially expressed following the BRD-K95655893_VEGF Receptor 3 Kinase Inhibitor, MAZ51_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ALG8 ALG8, alpha-1,3-glucosyltransferase
CA12 carbonic anhydrase XII
CD36 CD36 molecule (thrombospondin receptor)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COCH cochlin
CSRP2 cysteine and glycine-rich protein 2
FBL fibrillarin
FRY furry homolog (Drosophila)
GAB2 GRB2-associated binding protein 2
HOOK2 hook microtubule-tethering protein 2
HSPA1A heat shock 70kDa protein 1A
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
ODC1 ornithine decarboxylase 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PRDX2 peroxiredoxin 2
RGS5 regulator of G-protein signaling 5
SCGB2A2 secretoglobin, family 2A, member 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
STC2 stanniocalcin 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
TFPI2 tissue factor pathway inhibitor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TPBG trophoblast glycoprotein
VWF von Willebrand factor
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CCNE2 cyclin E2
CD1B CD1b molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHGB chromogranin B
CTSB cathepsin B
CTSS cathepsin S
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYTL1 cytokine-like 1
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
HEPH hephaestin
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HOPX HOP homeobox
HPRT1 hypoxanthine phosphoribosyltransferase 1
IGL immunoglobulin lambda locus
INHBA inhibin, beta A
LUM lumican
MAGEA3 melanoma antigen family A3
MCM6 minichromosome maintenance complex component 6
MFAP5 microfibrillar associated protein 5
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MUC5B mucin 5B, oligomeric mucus/gel-forming
NNMT nicotinamide N-methyltransferase
OAT ornithine aminotransferase
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDLIM3 PDZ and LIM domain 3
PRDX3 peroxiredoxin 3
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PSD3 pleckstrin and Sec7 domain containing 3
PSPH phosphoserine phosphatase
RFTN1 raftlin, lipid raft linker 1
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SNAP25 synaptosomal-associated protein, 25kDa
SULF1 sulfatase 1
TCTA T-cell leukemia translocation altered
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3