BRD-K95495709_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K95495709_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
CADM1 cell adhesion molecule 1
COCH cochlin
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EYA1 EYA transcriptional coactivator and phosphatase 1
FLNA filamin A, alpha
GNAS GNAS complex locus
H1F0 H1 histone family, member 0
HMOX1 heme oxygenase 1
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
MAP1B microtubule-associated protein 1B
MT1X metallothionein 1X
MT2A metallothionein 2A
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX11 SRY (sex determining region Y)-box 11
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
ANXA4 annexin A4
C2CD5 C2 calcium-dependent domain containing 5
C6ORF62 chromosome 6 open reading frame 62
CFB complement factor B
EIF1AX eukaryotic translation initiation factor 1A, X-linked
HSPA1A heat shock 70kDa protein 1A
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SPARCL1 SPARC-like 1 (hevin)
SRGN serglycin
TSPAN8 tetraspanin 8