BRD-K95435023_PHA-665752_HCC515_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K95435023_PHA-665752_HCC515_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ADGRG1 adhesion G protein-coupled receptor G1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
BEX1 brain expressed, X-linked 1
C5AR1 complement component 5a receptor 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CRIP1 cysteine-rich protein 1 (intestinal)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DAPK1 death-associated protein kinase 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FAM171A1 family with sequence similarity 171, member A1
FGB fibrinogen beta chain
FRY furry homolog (Drosophila)
GPX3 glutathione peroxidase 3
GRB14 growth factor receptor-bound protein 14
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
LY75 lymphocyte antigen 75
MAGEA3 melanoma antigen family A3
MAL mal, T-cell differentiation protein
MSLN mesothelin
MTSS1 metastasis suppressor 1
MUC1 mucin 1, cell surface associated
MX2 MX dynamin-like GTPase 2
MXRA5 matrix-remodelling associated 5
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NFE2L1 nuclear factor, erythroid 2-like 1
NRN1 neuritin 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PEG3 paternally expressed 3
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
SEPP1 selenoprotein P, plasma, 1
SNX11 sorting nexin 11
TGFBR3 transforming growth factor, beta receptor III
TNS1 tensin 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCND2 cyclin D2
CDC25B cell division cycle 25B
CEMIP cell migration inducing protein, hyaluronan binding
CKS2 CDC28 protein kinase regulatory subunit 2
CLEC2B C-type lectin domain family 2, member B
CRABP2 cellular retinoic acid binding protein 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL14 chemokine (C-X-C motif) ligand 14
CXCR4 chemokine (C-X-C motif) receptor 4
DUSP6 dual specificity phosphatase 6
EIF5A eukaryotic translation initiation factor 5A
EPCAM epithelial cell adhesion molecule
FOSL1 FOS-like antigen 1
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
IER3 immediate early response 3
KIAA0226L KIAA0226-like
KIF20A kinesin family member 20A
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMP7 matrix metallopeptidase 7
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PDE4B phosphodiesterase 4B, cAMP-specific
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PRKACB protein kinase, cAMP-dependent, catalytic, beta
S100A2 S100 calcium binding protein A2
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SPINK4 serine peptidase inhibitor, Kazal type 4
SPRY2 sprouty homolog 2 (Drosophila)
STK10 serine/threonine kinase 10
TFDP1 transcription factor Dp-1
TMEM158 transmembrane protein 158 (gene/pseudogene)