BRD-K95435023_PHA-665752_A549_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

89 genes differentially expressed following the BRD-K95435023_PHA-665752_A549_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG1 adhesion G protein-coupled receptor G1
ADGRG6 adhesion G protein-coupled receptor G6
ANGPT1 angiopoietin 1
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
BTBD3 BTB (POZ) domain containing 3
CBR3 carbonyl reductase 3
CDK19 cyclin-dependent kinase 19
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CES1 carboxylesterase 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
CRYAB crystallin, alpha B
CTGF connective tissue growth factor
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCN decorin
DSP desmoplakin
ERBB2 erb-b2 receptor tyrosine kinase 2
FMO2 flavin containing monooxygenase 2 (non-functional)
GADD45B growth arrest and DNA-damage-inducible, beta
HOXA5 homeobox A5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP7 insulin-like growth factor binding protein 7
IGKV1-5 immunoglobulin kappa variable 1-5
KRT7 keratin 7, type II
LPL lipoprotein lipase
MAP7 microtubule-associated protein 7
MFAP3L microfibrillar-associated protein 3-like
MYH10 myosin, heavy chain 10, non-muscle
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PHYH phytanoyl-CoA 2-hydroxylase
PLCB4 phospholipase C, beta 4
RPL38 ribosomal protein L38
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TIMP3 TIMP metallopeptidase inhibitor 3
TSPAN31 tetraspanin 31
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ARL4C ADP-ribosylation factor-like 4C
CALML3 calmodulin-like 3
CCND1 cyclin D1
CCND2 cyclin D2
COL14A1 collagen, type XIV, alpha 1
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
ELANE elastase, neutrophil expressed
EREG epiregulin
ETV1 ets variant 1
ETV5 ets variant 5
GPER1 G protein-coupled estrogen receptor 1
HAT1 histone acetyltransferase 1
HBB hemoglobin, beta
HP haptoglobin
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KLK10 kallikrein-related peptidase 10
KLK11 kallikrein-related peptidase 11
KLK7 kallikrein-related peptidase 7
LOC100505650 uncharacterized LOC100505650
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LTF lactotransferrin
MEIS2 Meis homeobox 2
MSLN mesothelin
NOLC1 nucleolar and coiled-body phosphoprotein 1
NT5E 5'-nucleotidase, ecto (CD73)
ODC1 ornithine decarboxylase 1
PDE4B phosphodiesterase 4B, cAMP-specific
PHLDA1 pleckstrin homology-like domain, family A, member 1
PI3 peptidase inhibitor 3, skin-derived
PRSS3 protease, serine, 3
RGS2 regulator of G-protein signaling 2
S100A9 S100 calcium binding protein A9
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SPRR1A small proline-rich protein 1A
SPRR3 small proline-rich protein 3
TCF4 transcription factor 4
TFF3 trefoil factor 3 (intestinal)
TFPI2 tissue factor pathway inhibitor 2
ZBTB18 zinc finger and BTB domain containing 18