BRD-K95196255_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-K95196255_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADGRG2 adhesion G protein-coupled receptor G2
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
AK4 adenylate kinase 4
ALDOC aldolase C, fructose-bisphosphate
ANOS1 anosmin 1
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C10ORF10 chromosome 10 open reading frame 10
C1R complement component 1, r subcomponent
CELF2 CUGBP, Elav-like family member 2
DDIT4 DNA-damage-inducible transcript 4
DUSP3 dual specificity phosphatase 3
EGLN3 egl-9 family hypoxia-inducible factor 3
ENO2 enolase 2 (gamma, neuronal)
FABP7 fatty acid binding protein 7, brain
GADD45B growth arrest and DNA-damage-inducible, beta
GPI glucose-6-phosphate isomerase
HCAR3 hydroxycarboxylic acid receptor 3
HK2 hexokinase 2
HMOX1 heme oxygenase 1
IL32 interleukin 32
INSIG2 insulin induced gene 2
KDM3A lysine (K)-specific demethylase 3A
LBH limb bud and heart development
LDHA lactate dehydrogenase A
LOXL2 lysyl oxidase-like 2
MAP1B microtubule-associated protein 1B
MT1F metallothionein 1F
MT1X metallothionein 1X
MXI1 MAX interactor 1, dimerization protein
NDRG1 N-myc downstream regulated 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAM peptidylglycine alpha-amidating monooxygenase
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PLTP phospholipid transfer protein
PNMA2 paraneoplastic Ma antigen 2
RNF167 ring finger protein 167
SCG5 secretogranin V
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SPAG4 sperm associated antigen 4
TGFA transforming growth factor, alpha
TMEM100 transmembrane protein 100
TMEM45A transmembrane protein 45A
VEGFA vascular endothelial growth factor A
YBX3 Y box binding protein 3

decreased expression

Symbol Name
CD200 CD200 molecule
CD24 CD24 molecule
CDH3 cadherin 3, type 1, P-cadherin (placental)
CENPA centromere protein A
CKS2 CDC28 protein kinase regulatory subunit 2
CRISP3 cysteine-rich secretory protein 3
CSTA cystatin A (stefin A)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ESR1 estrogen receptor 1
FLRT3 fibronectin leucine rich transmembrane protein 3
FMO2 flavin containing monooxygenase 2 (non-functional)
GATA3 GATA binding protein 3
GRIA2 glutamate receptor, ionotropic, AMPA 2
KANK1 KN motif and ankyrin repeat domains 1
KRT14 keratin 14, type I
KYNU kynureninase
MAP7 microtubule-associated protein 7
MNDA myeloid cell nuclear differentiation antigen
MTA1 metastasis associated 1
PDLIM5 PDZ and LIM domain 5
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
POSTN periostin, osteoblast specific factor
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
TOP2A topoisomerase (DNA) II alpha 170kDa
TPD52L1 tumor protein D52-like 1