BRD-K94991378_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K94991378_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AQP3 aquaporin 3 (Gill blood group)
ATF3 activating transcription factor 3
BEX4 brain expressed, X-linked 4
BTG2 BTG family, member 2
CAST calpastatin
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
COL11A1 collagen, type XI, alpha 1
DACH1 dachshund family transcription factor 1
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
FADS1 fatty acid desaturase 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FHOD3 formin homology 2 domain containing 3
G0S2 G0/G1 switch 2
GAGE3 G antigen 3
GRK5 G protein-coupled receptor kinase 5
GSTA1 glutathione S-transferase alpha 1
HBB hemoglobin, beta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
JUN jun proto-oncogene
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
LDLR low density lipoprotein receptor
MUC5B mucin 5B, oligomeric mucus/gel-forming
NR4A2 nuclear receptor subfamily 4, group A, member 2
PDE4DIP phosphodiesterase 4D interacting protein
PELI1 pellino E3 ubiquitin protein ligase 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RGS5 regulator of G-protein signaling 5
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SEC31A SEC31 homolog A (S. cerevisiae)
SIK1 salt-inducible kinase 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SNAI2 snail family zinc finger 2
THBS2 thrombospondin 2
TSC22D3 TSC22 domain family, member 3
TWIST1 twist family bHLH transcription factor 1
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
BCL2L1 BCL2-like 1
BSG basigin (Ok blood group)
C2CD5 C2 calcium-dependent domain containing 5
CA2 carbonic anhydrase II
CCNB2 cyclin B2
CD24 CD24 molecule
CD81 CD81 molecule
CLDN3 claudin 3
CYBA cytochrome b-245, alpha polypeptide
EPCAM epithelial cell adhesion molecule
HACD3 3-hydroxyacyl-CoA dehydratase 3
HMG20B high mobility group 20B
HOXA10 homeobox A10
LAPTM4B lysosomal protein transmembrane 4 beta
MFSD10 major facilitator superfamily domain containing 10
MMP7 matrix metallopeptidase 7
PARP2 poly (ADP-ribose) polymerase 2
PLK1 polo-like kinase 1
PODXL podocalyxin-like
PROM1 prominin 1
RNH1 ribonuclease/angiogenin inhibitor 1
UBE2S ubiquitin-conjugating enzyme E2S