BRD-K94544211_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

96 genes differentially expressed following the BRD-K94544211_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACPP acid phosphatase, prostate
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALOX5 arachidonate 5-lipoxygenase
ARG2 arginase 2
ARHGAP6 Rho GTPase activating protein 6
ARMCX2 armadillo repeat containing, X-linked 2
BHLHE41 basic helix-loop-helix family, member e41
C10ORF10 chromosome 10 open reading frame 10
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DNM1L dynamin 1-like
EDNRB endothelin receptor type B
FABP7 fatty acid binding protein 7, brain
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FAM63A family with sequence similarity 63, member A
FN1 fibronectin 1
GSDMB gasdermin B
HAPLN1 hyaluronan and proteoglycan link protein 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
LOC100505650 uncharacterized LOC100505650
LTB lymphotoxin beta (TNF superfamily, member 3)
LXN latexin
MAP7 microtubule-associated protein 7
MARCKS myristoylated alanine-rich protein kinase C substrate
MATN2 matrilin 2
MCAM melanoma cell adhesion molecule
MKNK1 MAP kinase interacting serine/threonine kinase 1
NEFH neurofilament, heavy polypeptide
NTS neurotensin
OLFM4 olfactomedin 4
PLA2G16 phospholipase A2, group XVI
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPAP2A phosphatidic acid phosphatase type 2A
PPAP2B phosphatidic acid phosphatase type 2B
PPIC peptidylprolyl isomerase C (cyclophilin C)
PRAME preferentially expressed antigen in melanoma
PRKD1 protein kinase D1
PTN pleiotrophin
QPCT glutaminyl-peptide cyclotransferase
RCAN1 regulator of calcineurin 1
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SPON1 spondin 1, extracellular matrix protein
TBX3 T-box 3
TFPI2 tissue factor pathway inhibitor 2
TMEM255A transmembrane protein 255A
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRIM2 tripartite motif containing 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ASPN asporin
ATP9A ATPase, class II, type 9A
C4BPA complement component 4 binding protein, alpha
CADM1 cell adhesion molecule 1
CALB1 calbindin 1, 28kDa
CDCA4 cell division cycle associated 4
CRISP3 cysteine-rich secretory protein 3
DSP desmoplakin
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FBN1 fibrillin 1
FOLR1 folate receptor 1 (adult)
GOLM1 golgi membrane protein 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
GSTA1 glutathione S-transferase alpha 1
HACD3 3-hydroxyacyl-CoA dehydratase 3
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
KRT6A keratin 6A, type II
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
PEG10 paternally expressed 10
PLEC plectin
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
POSTN periostin, osteoblast specific factor
PPIF peptidylprolyl isomerase F
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SDC1 syndecan 1
SPRR1B small proline-rich protein 1B
TOR1A torsin family 1, member A (torsin A)
UBE2E3 ubiquitin-conjugating enzyme E2E 3
ZNF586 zinc finger protein 586