BRD-K94544211_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

102 genes differentially expressed following the BRD-K94544211_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1C3 aldo-keto reductase family 1, member C3
ALDOC aldolase C, fructose-bisphosphate
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMIGO2 adhesion molecule with Ig-like domain 2
ASRGL1 asparaginase like 1
BACE2 beta-site APP-cleaving enzyme 2
BASP1 brain abundant, membrane attached signal protein 1
C3 complement component 3
CD200 CD200 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFD complement factor D (adipsin)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLIC5 chloride intracellular channel 5
COL1A1 collagen, type I, alpha 1
DDIT4 DNA-damage-inducible transcript 4
DHRS7 dehydrogenase/reductase (SDR family) member 7
DPYSL3 dihydropyrimidinase-like 3
DTX4 deltex 4, E3 ubiquitin ligase
DUSP1 dual specificity phosphatase 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FADS1 fatty acid desaturase 1
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
FOXO1 forkhead box O1
FOXO4 forkhead box O4
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GLRX glutaredoxin (thioltransferase)
GPRC5B G protein-coupled receptor, class C, group 5, member B
GSTA1 glutathione S-transferase alpha 1
HLA-B major histocompatibility complex, class I, B
HMOX1 heme oxygenase 1
IFI16 interferon, gamma-inducible protein 16
IFI27 interferon, alpha-inducible protein 27
IGFBP6 insulin-like growth factor binding protein 6
IL32 interleukin 32
INHBB inhibin, beta B
IRF9 interferon regulatory factor 9
KRT19 keratin 19, type I
KRT23 keratin 23, type I
KYNU kynureninase
LOXL2 lysyl oxidase-like 2
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMD monocyte to macrophage differentiation-associated
MX1 MX dynamin-like GTPase 1
OLFM4 olfactomedin 4
PDE4B phosphodiesterase 4B, cAMP-specific
PFKM phosphofructokinase, muscle
PGM1 phosphoglucomutase 1
PLIN2 perilipin 2
PPAP2C phosphatidic acid phosphatase type 2C
PRSS8 protease, serine, 8
PYGL phosphorylase, glycogen, liver
RHOQ ras homolog family member Q
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SCPEP1 serine carboxypeptidase 1
SELENBP1 selenium binding protein 1
SHB Src homology 2 domain containing adaptor protein B
SIRPA signal-regulatory protein alpha
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SOX11 SRY (sex determining region Y)-box 11
SYNGR3 synaptogyrin 3
SYNPO synaptopodin
SYT1 synaptotagmin I
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM45A transmembrane protein 45A
TMSB15A thymosin beta 15a
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VIM vimentin
VLDLR very low density lipoprotein receptor
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
AK4 adenylate kinase 4
CAST calpastatin
CDC25A cell division cycle 25A
CNOT7 CCR4-NOT transcription complex, subunit 7
CXCL13 chemokine (C-X-C motif) ligand 13
DBF4 DBF4 zinc finger
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
GMDS GDP-mannose 4,6-dehydratase
GRWD1 glutamate-rich WD repeat containing 1
HIST1H4C histone cluster 1, H4c
ICAM3 intercellular adhesion molecule 3
LIG1 ligase I, DNA, ATP-dependent
ODC1 ornithine decarboxylase 1
PBK PDZ binding kinase
PPIF peptidylprolyl isomerase F
RFC2 replication factor C (activator 1) 2, 40kDa
S100A2 S100 calcium binding protein A2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)