BRD-K94390040_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

56 genes differentially expressed following the BRD-K94390040_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
AMIGO2 adhesion molecule with Ig-like domain 2
CA12 carbonic anhydrase XII
CALML3 calmodulin-like 3
CD24 CD24 molecule
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DSP desmoplakin
DUSP4 dual specificity phosphatase 4
FADS1 fatty acid desaturase 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOOK2 hook microtubule-tethering protein 2
IDI1 isopentenyl-diphosphate delta isomerase 1
IGKV4-1 immunoglobulin kappa variable 4-1
INSIG1 insulin induced gene 1
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT6B keratin 6B, type II
LDLR low density lipoprotein receptor
MSMO1 methylsterol monooxygenase 1
MTMR11 myotubularin related protein 11
MYOF myoferlin
PPAP2B phosphatidic acid phosphatase type 2B
RBM47 RNA binding motif protein 47
RIN2 Ras and Rab interactor 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SPRR1A small proline-rich protein 1A
SQLE squalene epoxidase
SRRM2 serine/arginine repetitive matrix 2
THBS1 thrombospondin 1

decreased expression

Symbol Name
ASS1 argininosuccinate synthase 1
CCDC86 coiled-coil domain containing 86
CD99 CD99 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CP ceruloplasmin (ferroxidase)
EGFL6 EGF-like-domain, multiple 6
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GNAS GNAS complex locus
H2AFX H2A histone family, member X
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KRT7 keratin 7, type II
PEG10 paternally expressed 10
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRPF4 pre-mRNA processing factor 4
RAD23B RAD23 homolog B (S. cerevisiae)
RALGDS ral guanine nucleotide dissociation stimulator
TFPI2 tissue factor pathway inhibitor 2
VDAC1 voltage-dependent anion channel 1