BRD-K94294671_A-1065_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

108 genes differentially expressed following the BRD-K94294671_A-1065_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMOTL2 angiomotin like 2
AQP3 aquaporin 3 (Gill blood group)
ASS1 argininosuccinate synthase 1
ATP9A ATPase, class II, type 9A
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BHLHE41 basic helix-loop-helix family, member e41
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CALR calreticulin
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCNG2 cyclin G2
CDH3 cadherin 3, type 1, P-cadherin (placental)
CHN2 chimerin 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
DAAM1 dishevelled associated activator of morphogenesis 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DKK3 dickkopf WNT signaling pathway inhibitor 3
EFNA1 ephrin-A1
FXYD5 FXYD domain containing ion transport regulator 5
GADD45B growth arrest and DNA-damage-inducible, beta
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GATA3 GATA binding protein 3
GDF15 growth differentiation factor 15
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GSE1 Gse1 coiled-coil protein
HBP1 HMG-box transcription factor 1
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IFITM1 interferon induced transmembrane protein 1
JUND jun D proto-oncogene
KLF10 Kruppel-like factor 10
KLHDC2 kelch domain containing 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
METTL7A methyltransferase like 7A
MGLL monoglyceride lipase
MME membrane metallo-endopeptidase
NELL2 NEL-like 2 (chicken)
NT5E 5'-nucleotidase, ecto (CD73)
OPHN1 oligophrenin 1
PADI2 peptidyl arginine deiminase, type II
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PNMA2 paraneoplastic Ma antigen 2
RAP1GAP RAP1 GTPase activating protein
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RGS16 regulator of G-protein signaling 16
RTN2 reticulon 2
S100A7 S100 calcium binding protein A7
SCD5 stearoyl-CoA desaturase 5
SCG5 secretogranin V
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SRPX2 sushi-repeat containing protein, X-linked 2
SSPN sarcospan
TF transferrin
THBS2 thrombospondin 2
TLE2 transducin-like enhancer of split 2
TLN1 talin 1
TMEM176B transmembrane protein 176B
TRDV3 T cell receptor delta variable 3
ZIC1 Zic family member 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
CDC25A cell division cycle 25A
CHPT1 choline phosphotransferase 1
COASY CoA synthase
CPA3 carboxypeptidase A3 (mast cell)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DMBT1 deleted in malignant brain tumors 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EFNB2 ephrin-B2
ENO1 enolase 1, (alpha)
EXOSC4 exosome component 4
FKBP11 FK506 binding protein 11, 19 kDa
GRWD1 glutamate-rich WD repeat containing 1
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPH1 heat shock 105kDa/110kDa protein 1
IGKC immunoglobulin kappa constant
IGKV4-1 immunoglobulin kappa variable 4-1
IL6ST interleukin 6 signal transducer
LAPTM4B lysosomal protein transmembrane 4 beta
LTF lactotransferrin
MRPL42 mitochondrial ribosomal protein L42
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PGC progastricsin (pepsinogen C)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PMP22 peripheral myelin protein 22
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRPF4 pre-mRNA processing factor 4
RAB4A RAB4A, member RAS oncogene family
REEP5 receptor accessory protein 5
RGS2 regulator of G-protein signaling 2
SFTPD surfactant protein D
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLPI secretory leukocyte peptidase inhibitor
SRSF3 serine/arginine-rich splicing factor 3
STIP1 stress-induced phosphoprotein 1
TPSAB1 tryptase alpha/beta 1
TSPYL5 TSPY-like 5
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZW10 zw10 kinetochore protein