BRD-K94176593_TWS-119_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K94176593_TWS-119_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADRB2 adrenoceptor beta 2, surface
C14ORF132 chromosome 14 open reading frame 132
CD163 CD163 molecule
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
RPS4Y1 ribosomal protein S4, Y-linked 1
STAB1 stabilin 1
SYNM synemin, intermediate filament protein
TRIM29 tripartite motif containing 29
VSIG4 V-set and immunoglobulin domain containing 4
WWC3 WWC family member 3

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
CLDN4 claudin 4
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP2 dual specificity phosphatase 2
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EPCAM epithelial cell adhesion molecule
EREG epiregulin
FOSL1 FOS-like antigen 1
GDF15 growth differentiation factor 15
GULP1 GULP, engulfment adaptor PTB domain containing 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IER3 immediate early response 3
KRT18 keratin 18, type I
LYZ lysozyme
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MYC v-myc avian myelocytomatosis viral oncogene homolog
PLSCR4 phospholipid scramblase 4
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC25A46 solute carrier family 25, member 46
TMEM243 transmembrane protein 243, mitochondrial