BRD-K94173926_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K94173926_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
CBS cystathionine-beta-synthase
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EAPP E2F-associated phosphoprotein
FADS1 fatty acid desaturase 1
FN1 fibronectin 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HES1 hes family bHLH transcription factor 1
HIST1H2AC histone cluster 1, H2ac
HSPA6 heat shock 70kDa protein 6 (HSP70B')
INSIG1 insulin induced gene 1
ISYNA1 inositol-3-phosphate synthase 1
KRT19 keratin 19, type I
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO1D myosin ID
MYOF myoferlin
NFIL3 nuclear factor, interleukin 3 regulated
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PEG10 paternally expressed 10
PELI1 pellino E3 ubiquitin protein ligase 1
PHGDH phosphoglycerate dehydrogenase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PPAP2A phosphatidic acid phosphatase type 2A
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRAME preferentially expressed antigen in melanoma
PSAT1 phosphoserine aminotransferase 1
QPRT quinolinate phosphoribosyltransferase
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STC2 stanniocalcin 2
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AK1 adenylate kinase 1
CA2 carbonic anhydrase II
CAST calpastatin
FAM3C family with sequence similarity 3, member C
IL13RA2 interleukin 13 receptor, alpha 2
MCOLN1 mucolipin 1
MXRA7 matrix-remodelling associated 7
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PBX3 pre-B-cell leukemia homeobox 3
PURA purine-rich element binding protein A
S100A9 S100 calcium binding protein A9
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
TMEM45A transmembrane protein 45A
WSB2 WD repeat and SOCS box containing 2