BRD-K94012289_OSI-027_SKBR3_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K94012289_OSI-027_SKBR3_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOLD1 apolipoprotein L domain containing 1
BCL6 B-cell CLL/lymphoma 6
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFLAR CASP8 and FADD-like apoptosis regulator
DLK1 delta-like 1 homolog (Drosophila)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FOXO3 forkhead box O3
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPNMB glycoprotein (transmembrane) nmb
GRB7 growth factor receptor-bound protein 7
HBP1 HMG-box transcription factor 1
HMGB2 high mobility group box 2
HNMT histamine N-methyltransferase
IGFBP7 insulin-like growth factor binding protein 7
IL6ST interleukin 6 signal transducer
IQCG IQ motif containing G
KIAA0355 KIAA0355
KIAA1033 KIAA1033
LGALS8 lectin, galactoside-binding, soluble, 8
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MX2 MX dynamin-like GTPase 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYLK myosin light chain kinase
MYOF myoferlin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PEG3 paternally expressed 3
PSD3 pleckstrin and Sec7 domain containing 3
S100A11 S100 calcium binding protein A11
SH3BGRL SH3 domain binding glutamate-rich protein like
SRGN serglycin
SRPK2 SRSF protein kinase 2
STC2 stanniocalcin 2
SYNM synemin, intermediate filament protein
TFRC transferrin receptor
TGIF1 TGFB-induced factor homeobox 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNC tenascin C
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
AKR1C3 aldo-keto reductase family 1, member C3
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
CD69 CD69 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLIC5 chloride intracellular channel 5
COTL1 coactosin-like F-actin binding protein 1
CTSH cathepsin H
CXCL9 chemokine (C-X-C motif) ligand 9
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCN decorin
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EAF2 ELL associated factor 2
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FOLR1 folate receptor 1 (adult)
FZD7 frizzled class receptor 7
G0S2 G0/G1 switch 2
GATA2 GATA binding protein 2
GPX3 glutathione peroxidase 3
HBB hemoglobin, beta
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IDO1 indoleamine 2,3-dioxygenase 1
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IRF8 interferon regulatory factor 8
JCHAIN joining chain of multimeric IgA and IgM
MALL mal, T-cell differentiation protein-like
PEA15 phosphoprotein enriched in astrocytes 15
PLAC8 placenta-specific 8
PODXL podocalyxin-like
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGCC regulator of cell cycle
SFTPC surfactant protein C
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2