BRD-K94012289_OSI-027_PC3_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K94012289_OSI-027_PC3_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADGRG6 adhesion G protein-coupled receptor G6
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOD apolipoprotein D
ATP11B ATPase, class VI, type 11B
BEX1 brain expressed, X-linked 1
CLDN3 claudin 3
CTGF connective tissue growth factor
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
GSN gelsolin
HIST1H2BG histone cluster 1, H2bg
HMGA2 high mobility group AT-hook 2
IFI27 interferon, alpha-inducible protein 27
IFIH1 interferon induced with helicase C domain 1
KLK11 kallikrein-related peptidase 11
KLK6 kallikrein-related peptidase 6
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LTBP3 latent transforming growth factor beta binding protein 3
MAGED1 melanoma antigen family D1
MAOB monoamine oxidase B
MGP matrix Gla protein
MX1 MX dynamin-like GTPase 1
MYOF myoferlin
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NET1 neuroepithelial cell transforming 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRUNE2 prune homolog 2 (Drosophila)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS4 regulator of G-protein signaling 4
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRAPPC6A trafficking protein particle complex 6A

decreased expression

Symbol Name
ADM adrenomedullin
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA12 carbonic anhydrase XII
CHN1 chimerin 1
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
COL7A1 collagen, type VII, alpha 1
CSTA cystatin A (stefin A)
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL5 chemokine (C-X-C motif) ligand 5
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT4 DNA-damage-inducible transcript 4
FADS1 fatty acid desaturase 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
KDM3A lysine (K)-specific demethylase 3A
KRT17 keratin 17, type I
MAGEA6 melanoma antigen family A6
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
ODC1 ornithine decarboxylase 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A8 S100 calcium binding protein A8
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNAI2 snail family zinc finger 2
TFRC transferrin receptor
TRBC1 T cell receptor beta constant 1
VEGFA vascular endothelial growth factor A
WNT5A wingless-type MMTV integration site family, member 5A