BRD-K94012289_OSI-027_MDAMB231_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

50 genes differentially expressed following the BRD-K94012289_OSI-027_MDAMB231_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
CD59 CD59 molecule, complement regulatory protein
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CTSA cathepsin A
DOK5 docking protein 5
FABP4 fatty acid binding protein 4, adipocyte
GPX4 glutathione peroxidase 4
GSN gelsolin
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGAV integrin, alpha V
JAG1 jagged 1
KLHL24 kelch-like family member 24
KRT23 keratin 23, type I
MDK midkine (neurite growth-promoting factor 2)
MMD monocyte to macrophage differentiation-associated
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
RB1CC1 RB1-inducible coiled-coil 1
RTN2 reticulon 2
SDCBP syndecan binding protein (syntenin)
SNAI2 snail family zinc finger 2
SQSTM1 sequestosome 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TFPI2 tissue factor pathway inhibitor 2
TPP1 tripeptidyl peptidase I
WT1 Wilms tumor 1
ZFAND5 zinc finger, AN1-type domain 5

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCND2 cyclin D2
CDC25A cell division cycle 25A
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
FEN1 flap structure-specific endonuclease 1
GINS2 GINS complex subunit 2 (Psf2 homolog)
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GRB14 growth factor receptor-bound protein 14
H2AFX H2A histone family, member X
HSPA4L heat shock 70kDa protein 4-like
ICMT isoprenylcysteine carboxyl methyltransferase
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
LTF lactotransferrin
MAGEA6 melanoma antigen family A6
MALL mal, T-cell differentiation protein-like
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2