BRD-K94012289_OSI-027_MCF7_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K94012289_OSI-027_MCF7_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
C5 complement component 5
CCND2 cyclin D2
CFD complement factor D (adipsin)
CLEC2B C-type lectin domain family 2, member B
COL4A5 collagen, type IV, alpha 5
DAPK1 death-associated protein kinase 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLK1 delta-like 1 homolog (Drosophila)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FKBP11 FK506 binding protein 11, 19 kDa
FLNA filamin A, alpha
GOLM1 golgi membrane protein 1
GPM6B glycoprotein M6B
HBP1 HMG-box transcription factor 1
MAN2B1 mannosidase, alpha, class 2B, member 1
MTSS1 metastasis suppressor 1
NPTX2 neuronal pentraxin II
PBX3 pre-B-cell leukemia homeobox 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSD3 pleckstrin and Sec7 domain containing 3
RPS4Y1 ribosomal protein S4, Y-linked 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM45A transmembrane protein 45A
TPD52 tumor protein D52
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AQP1 aquaporin 1 (Colton blood group)
CDC25A cell division cycle 25A
COL3A1 collagen, type III, alpha 1
FOLR1 folate receptor 1 (adult)
GBP1 guanylate binding protein 1, interferon-inducible
HBB hemoglobin, beta
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
IDO1 indoleamine 2,3-dioxygenase 1
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ISG15 ISG15 ubiquitin-like modifier
KYNU kynureninase
LAMP3 lysosomal-associated membrane protein 3
MMP7 matrix metallopeptidase 7
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRKD3 protein kinase D3
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SNAP25 synaptosomal-associated protein, 25kDa
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TOR1A torsin family 1, member A (torsin A)