BRD-K94012289_OSI-027_MCF7_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

111 genes differentially expressed following the BRD-K94012289_OSI-027_MCF7_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ANXA4 annexin A4
BTG2 BTG family, member 2
C6ORF48 chromosome 6 open reading frame 48
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CCNG2 cyclin G2
CDK19 cyclin-dependent kinase 19
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CHN1 chimerin 1
CLEC2B C-type lectin domain family 2, member B
EIF4B eukaryotic translation initiation factor 4B
ERBB2 erb-b2 receptor tyrosine kinase 2
FOXO4 forkhead box O4
GLTSCR2 glioma tumor suppressor candidate region gene 2
GPNMB glycoprotein (transmembrane) nmb
HBP1 HMG-box transcription factor 1
HIST1H2AC histone cluster 1, H2ac
HIST3H2A histone cluster 3, H2a
IFITM1 interferon induced transmembrane protein 1
IGFBP7 insulin-like growth factor binding protein 7
KDM3A lysine (K)-specific demethylase 3A
KIZ kizuna centrosomal protein
LETMD1 LETM1 domain containing 1
LYN LYN proto-oncogene, Src family tyrosine kinase
LYZ lysozyme
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MARCKSL1 MARCKS-like 1
MMP7 matrix metallopeptidase 7
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MXI1 MAX interactor 1, dimerization protein
NUPR1 nuclear protein, transcriptional regulator, 1
OPHN1 oligophrenin 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PIGP phosphatidylinositol glycan anchor biosynthesis, class P
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PNRC1 proline-rich nuclear receptor coactivator 1
QARS glutaminyl-tRNA synthetase
RAB38 RAB38, member RAS oncogene family
RALGDS ral guanine nucleotide dissociation stimulator
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGS10 regulator of G-protein signaling 10
RNF130 ring finger protein 130
SAMD4A sterile alpha motif domain containing 4A
SKAP2 src kinase associated phosphoprotein 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPATA20 spermatogenesis associated 20
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TMSB15A thymosin beta 15a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPP1 tripeptidyl peptidase I
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACLY ATP citrate lyase
ACOT7 acyl-CoA thioesterase 7
CA12 carbonic anhydrase XII
CD58 CD58 molecule
CDC42 cell division cycle 42
CDC6 cell division cycle 6
CLU clusterin
DCN decorin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHCR24 24-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
ENO1 enolase 1, (alpha)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGFR3 fibroblast growth factor receptor 3
GALE UDP-galactose-4-epimerase
GINS2 GINS complex subunit 2 (Psf2 homolog)
HAL histidine ammonia-lyase
HAT1 histone acetyltransferase 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLV3-19 immunoglobulin lambda variable 3-19
IL13RA2 interleukin 13 receptor, alpha 2
LAMP3 lysosomal-associated membrane protein 3
MFAP3L microfibrillar-associated protein 3-like
MSRB1 methionine sulfoxide reductase B1
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NQO1 NAD(P)H dehydrogenase, quinone 1
PGD phosphogluconate dehydrogenase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRDX1 peroxiredoxin 1
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
RFC2 replication factor C (activator 1) 2, 40kDa
RGS4 regulator of G-protein signaling 4
RPL39L ribosomal protein L39-like
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A2 S100 calcium binding protein A2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TFRC transferrin receptor
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TMPO thymopoietin
TRAC T cell receptor alpha constant
TUBB6 tubulin, beta 6 class V
TUBG1 tubulin, gamma 1